Ventilator-associated pneumonia in adults: a narrative review

L Papazian, M Klompas, CE Luyt - Intensive care medicine, 2020 - Springer
Ventilator-associated pneumonia (VAP) is one of the most frequent ICU-acquired infections.
Reported incidences vary widely from 5 to 40% depending on the setting and diagnostic …

Antibiotic treatment of biofilm infections

O Ciofu, E Rojo‐Molinero, MD Macià, A Oliver - Apmis, 2017 - Wiley Online Library
Bacterial biofilms are associated with a wide range of infections, from those related to
exogenous devices, such as catheters or prosthetic joints, to chronic tissue infections such …

Pulmonary infections complicating ARDS

CE Luyt, L Bouadma, AC Morris, JA Dhanani… - Intensive care …, 2020 - Springer
Pulmonary infection is one of the main complications occurring in patients suffering from
acute respiratory distress syndrome (ARDS). Besides traditional risk factors, dysregulation of …

Antibiotic stewardship in the intensive care unit

CE Luyt, N Bréchot, JL Trouillet, J Chastre - Critical care, 2014 - Springer
The rapid emergence and dissemination of antimicrobial-resistant microorganisms in ICUs
worldwide constitute a problem of crisis dimensions. The root causes of this problem are …

Management of adults with hospital-acquired and ventilator-associated pneumonia: 2016 clinical practice guidelines by the Infectious Diseases Society of America …

AC Kalil, ML Metersky, M Klompas… - Clinical infectious …, 2016 - academic.oup.com
It is important to realize that guidelines cannot always account for individual variation among
patients. They are not intended to supplant physician judgment with respect to particular …

[HTML][HTML] Hospital-acquired pneumonia in ICU

M Leone, L Bouadma, B Bouhemad, O Brissaud… - … Critical Care & Pain …, 2018 - Elsevier
Abstract The French Society of Anesthesia and Intensive Care Medicine and the French
Society of Intensive Care edited guidelines focused on hospital-acquired pneumonia (HAP) …

[HTML][HTML] Management of KPC-producing Klebsiella pneumoniae infections

M Bassetti, DR Giacobbe, H Giamarellou… - Clinical Microbiology …, 2018 - Elsevier
Background Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae (KPC-
KP) has become one of the most important contemporary pathogens, especially in endemic …

A randomized trial of the amikacin fosfomycin inhalation system for the adjunctive therapy of Gram-negative ventilator-associated pneumonia: IASIS Trial

MH Kollef, JD Ricard, D Roux, B Francois, E Ischaki… - Chest, 2017 - Elsevier
Background Clinical failures in ventilator-associated pneumonia (VAP) caused by gram-
negative bacteria are common and associated with substantial morbidity, mortality, and …

Advances in antibiotic therapy in the critically ill

JL Vincent, M Bassetti, B François, G Karam, J Chastre… - Critical Care, 2016 - Springer
Infections occur frequently in critically ill patients and their management can be challenging
for various reasons, including delayed diagnosis, difficulties identifying causative …

Management of multidrug resistant Gram-negative bacilli infections in solid organ transplant recipients: SET/GESITRA-SEIMC/REIPI recommendations

JM Aguado, JT Silva, M Fernández-Ruiz… - Transplantation …, 2018 - Elsevier
Solid organ transplant (SOT) recipients are especially at risk of developing infections by
multidrug resistant (MDR) Gram-negative bacilli (GNB), as they are frequently exposed to …