Signaling pathways in brain ischemia: Mechanisms and therapeutic implications
W Lin, XY Zhao, J Cheng, L Li, Q Jiang… - Pharmacology & …, 2023 - Elsevier
Ischemic stroke occurs when the arteries supplying blood to the brain are narrowed or
blocked, inducing damage to brain tissue due to a lack of blood supply. One effective way to …
blocked, inducing damage to brain tissue due to a lack of blood supply. One effective way to …
[HTML][HTML] Stem cell-based ischemic stroke therapy: Novel modifications and clinical challenges
Y Sun, X Jiang, J Gao - Asian Journal of Pharmaceutical Sciences, 2023 - Elsevier
Ischemic stroke (IS) causes severe disability and high mortality worldwide. Stem cell (SC)
therapy exhibits unique therapeutic potential for IS that differs from current treatments. SC's …
therapy exhibits unique therapeutic potential for IS that differs from current treatments. SC's …
[HTML][HTML] Regulation of extracellular vesicle-mediated immune responses against antigen-specific presentation
Y Matsuzaka, R Yashiro - Vaccines, 2022 - mdpi.com
Extracellular vesicles (EVs) produced by various immune cells, including B and T cells,
macrophages, dendritic cells (DCs), natural killer (NK) cells, and mast cells, mediate …
macrophages, dendritic cells (DCs), natural killer (NK) cells, and mast cells, mediate …
Exosomes derived from hypoxia-preconditioned mesenchymal stem cells (hypoMSCs-Exo): advantages in disease treatment
J Dong, B Wu, W Tian - Cell and Tissue Research, 2023 - Springer
Mesenchymal stem cells (MSCs)-based therapy has been reported to be a potential
approach to treat various diseases and the paracrine role might be the underlying …
approach to treat various diseases and the paracrine role might be the underlying …
[HTML][HTML] Regulatory Effects of Three-Dimensional Cultured Lipopolysaccharide-Pretreated Periodontal Ligament Stem Cell-Derived Secretome on Macrophages
Y Su, S Ai, Y Shen, W Cheng, C Xu, L Sui… - International Journal of …, 2023 - mdpi.com
Phenotypic transformation of macrophages plays important immune response roles in the
occurrence, development and regression of periodontitis. Under inflammation or other …
occurrence, development and regression of periodontitis. Under inflammation or other …
Effect of metformin on epidermal neural crest stem cells and their potential application in ameliorating paclitaxel-induced neurotoxicity phenotype
Abstract Aims Epidermal Neural Crest Stem Cells (EPI-NCSCs) have emerged as
prospective ideal candidates to meet the fundamental requirements of cell-based therapies …
prospective ideal candidates to meet the fundamental requirements of cell-based therapies …
Dual impacts of mesenchymal stem cell-derived exosomes on cancer cells: unravelling complex interactions
Mesenchymal stem cells (MSCs) are multipotent, self-renewing stromal cells found in a
variety of adult tissues. MSCs possess a remarkable ability to migrate towards tumor sites …
variety of adult tissues. MSCs possess a remarkable ability to migrate towards tumor sites …
[HTML][HTML] Inhibition of LPS‑induced NLRP3 inflammasome activation by stem cell‑conditioned culture media in human gingival epithelial cells
H Li, L Sun, Y Wang - Molecular Medicine Reports, 2023 - spandidos-publications.com
Abstract Interleukin (IL)‑1β is a pathogenic factor associated with the destruction of
periodontal tissue in periodontitis. IL‑1β processing is regulated by cytosolic machinery …
periodontal tissue in periodontitis. IL‑1β processing is regulated by cytosolic machinery …
Secretome of EMSCs neutralizes LPS‑induced acute lung injury via aerosol administration
J Tan, Z Zhuo, X Wang, Y Zhang… - International …, 2023 - spandidos-publications.com
Ectodermal mesenchymal stem cells (EMSCs) are cells harvested from the stem cell niche
(nasal mucosa) with high therapeutic potential. To the best of our knowledge, however, the …
(nasal mucosa) with high therapeutic potential. To the best of our knowledge, however, the …
Research progress and challenges of stem cell therapy for ischemic stroke
Z Cha, Y Qiao, Q Lu, Q Wang, X Lu… - Frontiers in Cell and …, 2024 - frontiersin.org
Ischemic stroke is a significant global cause of death and disability. Currently, treatment
options for acute ischemic stroke are limited to intravenous thrombolysis and mechanical …
options for acute ischemic stroke are limited to intravenous thrombolysis and mechanical …