[HTML][HTML] The role of thymoquinone in inflammatory response in chronic diseases

Y Liu, L Huang, MY Kim, JY Cho - International Journal of Molecular …, 2022 - mdpi.com
Anti-inflammatory therapies have been shown to be effective in the prevention of various
cardiovascular diseases, tumors, and cancer complications. Thymoquinone (TQ), the main …

Protective effects of fucoidan against kidney diseases: Pharmacological insights and future perspectives

MS Zahan, A Hasan, MDH Rahman, KN Meem… - International Journal of …, 2022 - Elsevier
Chronic kidney disease (CKD) is a major public health concern that costs millions of lives
worldwide. Natural products are consistently being explored for the development of novel …

[HTML][HTML] Ameliorative effect of Nigella sativa conjugated silver nanoparticles against chromium-induced hepatotoxicity and renal toxicity in mice

T Nauroze, S Ali, L Kanwal, C Ara, TA Mughal… - Saudi Journal of …, 2023 - Elsevier
Hexavalent chromium induces oxidative stress in the liver and kidney. Therefore an in vivo
study was designed to investigate the modulatory effect of biosynthesized AgNP against Cr …

[HTML][HTML] Zygo-Albuside A: New Saponin from Zygophyllum album L. with Significant Antioxidant, Anti-Inflammatory and Antiapoptotic Effects against Methotrexate …

RFA Abdelhameed, SA Fattah, ET Mehanna… - International Journal of …, 2022 - mdpi.com
Chemical investigation of the crude extract of the aerial part of Zygophyllum album L.(Z.
album) led to the isolation of a new saponin, Zygo-albuside A (7), together with seven known …

[HTML][HTML] Natural products for kidney disease treatment: Focus on targeting mitochondrial dysfunction

J Huang, Y Liang, L Zhou - Frontiers in Pharmacology, 2023 - frontiersin.org
The patients with kidney diseases are increasing rapidly all over the world. With the rich
abundance of mitochondria, kidney is an organ with a high consumption of energy. Hence …

[HTML][HTML] Potentials of curcumin against polycystic ovary syndrome: Pharmacological insights and therapeutic promises

T Akter, MS Zahan, N Nawal, MH Rahman, TN Tanjum… - Heliyon, 2023 - cell.com
Polycystic ovary syndrome (PCOS) is a common hormonal disorder among women (4%–
20%) when the ovaries create abnormally high levels of androgens, the male sex hormones …

The effect of Nigella sativa oil-and wheat germ oil-loaded metal organic frameworks on chronic murine toxoplasmosis

OS Mohammad, HM El Naggar, HF Abdelmaksoud… - Acta Tropica, 2023 - Elsevier
Abstract Treatment of chronic toxoplasmosis is challenging as the available drugs are
effective only in the acute stage. Therefore, the current study aimed to investigate Nigella …

3-Demethyl-2-geranyl-4-prenylbellidifoline, a natural xanthone with diuretic and kidney protective properties

LNB Mariano, T Boeing, VC Filho… - Journal of Pharmacy …, 2024 - academic.oup.com
Objectives The diuretic and kidney protective effect of the 3-demethyl-2-geranyl-4-
prenylbellidifoline (DGP) were evaluated in rats. Methods The normotensive (NTR) and …

Pollutants to Pathogens: The Role of Heavy Metals in Modulating TGF-β Signaling and Lung Cancer Risk

AA Bhat, E Moglad, P Bansal, H Kaur, M Deorari… - … -Research and Practice, 2024 - Elsevier
Lung cancer is a malignant tumor that develops in the lungs due to the uncontrolled growth
of aberrant cells. Heavy metals, such as arsenic, cadmium, mercury, and lead, are metallic …

HDAC inhibition by Nigella sativa L. sprouts extract in hepatocellular carcinoma: an approach to study anti-cancer potential

A Algaissi, H Tabassum, E Khan… - Journal of …, 2023 - Taylor & Francis
A wide variety of natural products have been widely used in chemoprevention therapy
because they have antioxidant, anti-inflammatory, and anticancer activity. In the present …