[HTML][HTML] Epigenomic insights into common human disease pathology
CG Bell - Cellular and Molecular Life Sciences, 2024 - Springer
The epigenome—the chemical modifications and chromatin-related packaging of the
genome—enables the same genetic template to be activated or repressed in different …
genome—enables the same genetic template to be activated or repressed in different …
[HTML][HTML] Quantifying the stochastic component of epigenetic aging
DNA methylation clocks can accurately estimate chronological age and, to some extent, also
biological age, yet the process by which age-associated DNA methylation (DNAm) changes …
biological age, yet the process by which age-associated DNA methylation (DNAm) changes …
Twin-based Mendelian Randomization Analyses Highlight Smoking's Effects on Blood DNA Methylation, with Putative Reverse Causation
Epigenome-wide association studies (EWAS) aim to identify differentially methylated loci
associated with complex traits and disorders. EWAS of cigarette smoking shows some of the …
associated with complex traits and disorders. EWAS of cigarette smoking shows some of the …
Intergenerational transmission of complex traits and the offspring methylome
The genetic makeup of parents can directly or indirectly affect their offspring phenome
through genetic transmission or via the environment that is influenced by parental heritable …
through genetic transmission or via the environment that is influenced by parental heritable …
[HTML][HTML] Lifestyle differences between co-twins are associated with decreased similarity in their internal and external exposome profiles
Whether differences in lifestyle between co-twins are reflected in differences in their internal
or external exposome profiles remains largely underexplored. We therefore investigated …
or external exposome profiles remains largely underexplored. We therefore investigated …
[PDF][PDF] SMOKING AND GENOTYPE: MODERN STATE OF THE ISSUE
AA Arslanbekovich, KS Jamilovna - MEDICAL SCIENCES - colloquium-journal.org
Smoking is a serious medical and social problem affecting the development of cancer, lung
and heart diseases. It leads to mutations in lung tissues and the addition of many genetic …
and heart diseases. It leads to mutations in lung tissues and the addition of many genetic …