The immunology of takotsubo syndrome

KRQ Lim, DL Mann, T Kenzaka, T Hayashi - Frontiers in immunology, 2023 - frontiersin.org
Takotsubo syndrome (TTS) is a disorder characterized by transient cardiac dysfunction with
ventricular regional wall motion abnormalities, primarily thought to be caused by the effects …

Life-Threatening Arrhythmias in Patients With Takotsubo Syndrome: Insights Into Pathophysiology and Treatment Innovations

G La Vecchia, MG Del Buono, T Sanna… - JACC: Clinical …, 2024 - Elsevier
Takotsubo syndrome (TTS) is a reversible form of acute myocardial injury due to a
neurocardiogenic mechanism associated with a relevant risk for life-threatening ventricular …

α2δ-1 as a New Target for Immunosuppressant-Induced Hypertension

A Hinton Jr, A Kirabo - Circulation Research, 2023 - Am Heart Assoc
Given that calcineurin exists in immune T cells, it is frequently targeted in transplants and
autoimmune diseases, necessitating its inhibition. 1 Recent studies have shown that …

Liraglutide Protects Cardiomyocytes against Isoprenaline-Induced Apoptosis in Experimental Takotsubo Syndrome

Z Bajic, T Sobot, L Amidzic, N Vojinovic, S Jovicic… - Biomedicines, 2024 - mdpi.com
Takotsubo syndrome (TTS) is a stress-induced cardiomyopathy, characterized by an
increased concentration of catecholamines, free radicals, and inflammatory cytokines …

Ca2+/calmodulin‐dependent kinase IIδC‐induced chronic heart failure does not depend on sarcoplasmic reticulum Ca2+ leak

M Dewenter, T Seitz, JH Steinbrecher… - ESC Heart …, 2024 - Wiley Online Library
Abstract Aims Hyperactivity of Ca2+/calmodulin‐dependent protein kinase II (CaMKII) has
emerged as a central cause of pathologic remodelling in heart failure. It has been suggested …

Insulin resistance in Takotsubo syndrome

B Bruns, M Joos, N Elsous, HA Katus… - ESC Heart …, 2024 - Wiley Online Library
Aims Takotsubo syndrome (TTS) is an acute heart failure (AHF) syndrome mimicking the
symptoms of acute myocardial infarction. Impaired outcome has been shown, making risk …