Modulation of dopamine tone induces frequency shifts in cortico-basal ganglia beta oscillations

L Iskhakova, P Rappel, M Deffains, G Fonar… - Nature …, 2021 - nature.com
Βeta oscillatory activity (human: 13–35 Hz; primate: 8–24 Hz) is pervasive within the cortex
and basal ganglia. Studies in Parkinson's disease patients and animal models suggest that …

Threat gates visual aversion via theta activity in Tachykinergic neurons

M Tsuji, Y Nishizuka, K Emoto - Nature Communications, 2023 - nature.com
Animals must adapt sensory responses to an ever-changing environment for survival. Such
sensory modulation is especially critical in a threatening situation, in which animals often …

A role for the subthalamic nucleus in aversive learning

GP Serra, A Guillaumin, B Vlcek, L Delgado-Zabalza… - Cell Reports, 2023 - cell.com
The subthalamic nucleus (STN) is critical for behavioral control; its dysregulation
consequently correlated with neurological and neuropsychiatric disorders, including …

Non-Faradaic optoelectrodes for safe electrical neuromodulation

J Chen, Y Liu, F Chen, M Guo, J Zhou, P Fu… - Nature …, 2024 - nature.com
Nanoscale optoelectrodes hold the potential to stimulate optically individual neurons and
intracellular organelles, a challenge that demands both a high-density of photoelectron …

Subthalamic deep brain stimulation of an anatomically detailed model of the human hyperdirect pathway

CS Bingham, CC McIntyre - Journal of Neurophysiology, 2022 - journals.physiology.org
The motor hyperdirect pathway (HDP) is considered a key target in the treatment of
Parkinson's disease with subthalamic deep brain stimulation (DBS). This hypothesis is …

Deep brain stimulation of the habenula: systematic review of the literature and clinical trial registries

J Germann, M Mameli, GJB Elias, A Loh, A Taha… - Frontiers in …, 2021 - frontiersin.org
The habenula is a small bilateral epithalamic structure that plays a key role in the regulation
of the main monoaminergic systems. It is implicated in many aspects of behavior such as …

[HTML][HTML] Deep brain stimulation of terminating axons

KL Bower, CC McIntyre - Brain stimulation, 2020 - Elsevier
Background Deep brain stimulation (DBS) of the subthalamic region is an established
treatment for the motor symptoms of Parkinson's disease. Several types of neural elements …

[HTML][HTML] Image-based biophysical modeling predicts cortical potentials evoked with subthalamic deep brain stimulation

B Howell, F Isbaine, JT Willie, E Opri, RE Gross… - Brain Stimulation, 2021 - Elsevier
Background Subthalamic deep brain stimulation (DBS) is an effective surgical treatment for
Parkinson's disease and continues to advance technologically with an enormous parameter …

Nanoscale Magneto-mechanical-genetics of Deep Brain Neurons Reversing Motor Deficits in Parkinsonian Mice

W Shin, Y Lee, J Lim, Y Lee, JD Lah, S Lee, J Lee… - Nano …, 2023 - ACS Publications
Here, we introduce the magneto-mechanical-genetic (MMG)-driven wireless deep brain
stimulation (DBS) using magnetic nanostructures for therapeutic benefits in the mouse …

Subthalamic neurons interact with nigral dopaminergic neurons to regulate movement in mice

JP Fan, X Zhang, Y Han, Y Ji, WX Gu, HC Wu… - Acta …, 2023 - Wiley Online Library
Aim This study aims to address the role of the interaction between subthalamic (STN)
neurons and substantia nigra pars compacta (SNc) dopaminergic (DA) neurons in …