Modulation of dopamine tone induces frequency shifts in cortico-basal ganglia beta oscillations
Βeta oscillatory activity (human: 13–35 Hz; primate: 8–24 Hz) is pervasive within the cortex
and basal ganglia. Studies in Parkinson's disease patients and animal models suggest that …
and basal ganglia. Studies in Parkinson's disease patients and animal models suggest that …
Threat gates visual aversion via theta activity in Tachykinergic neurons
Animals must adapt sensory responses to an ever-changing environment for survival. Such
sensory modulation is especially critical in a threatening situation, in which animals often …
sensory modulation is especially critical in a threatening situation, in which animals often …
A role for the subthalamic nucleus in aversive learning
GP Serra, A Guillaumin, B Vlcek, L Delgado-Zabalza… - Cell Reports, 2023 - cell.com
The subthalamic nucleus (STN) is critical for behavioral control; its dysregulation
consequently correlated with neurological and neuropsychiatric disorders, including …
consequently correlated with neurological and neuropsychiatric disorders, including …
Non-Faradaic optoelectrodes for safe electrical neuromodulation
J Chen, Y Liu, F Chen, M Guo, J Zhou, P Fu… - Nature …, 2024 - nature.com
Nanoscale optoelectrodes hold the potential to stimulate optically individual neurons and
intracellular organelles, a challenge that demands both a high-density of photoelectron …
intracellular organelles, a challenge that demands both a high-density of photoelectron …
Subthalamic deep brain stimulation of an anatomically detailed model of the human hyperdirect pathway
CS Bingham, CC McIntyre - Journal of Neurophysiology, 2022 - journals.physiology.org
The motor hyperdirect pathway (HDP) is considered a key target in the treatment of
Parkinson's disease with subthalamic deep brain stimulation (DBS). This hypothesis is …
Parkinson's disease with subthalamic deep brain stimulation (DBS). This hypothesis is …
Deep brain stimulation of the habenula: systematic review of the literature and clinical trial registries
The habenula is a small bilateral epithalamic structure that plays a key role in the regulation
of the main monoaminergic systems. It is implicated in many aspects of behavior such as …
of the main monoaminergic systems. It is implicated in many aspects of behavior such as …
[HTML][HTML] Deep brain stimulation of terminating axons
KL Bower, CC McIntyre - Brain stimulation, 2020 - Elsevier
Background Deep brain stimulation (DBS) of the subthalamic region is an established
treatment for the motor symptoms of Parkinson's disease. Several types of neural elements …
treatment for the motor symptoms of Parkinson's disease. Several types of neural elements …
[HTML][HTML] Image-based biophysical modeling predicts cortical potentials evoked with subthalamic deep brain stimulation
Background Subthalamic deep brain stimulation (DBS) is an effective surgical treatment for
Parkinson's disease and continues to advance technologically with an enormous parameter …
Parkinson's disease and continues to advance technologically with an enormous parameter …
Nanoscale Magneto-mechanical-genetics of Deep Brain Neurons Reversing Motor Deficits in Parkinsonian Mice
W Shin, Y Lee, J Lim, Y Lee, JD Lah, S Lee, J Lee… - Nano …, 2023 - ACS Publications
Here, we introduce the magneto-mechanical-genetic (MMG)-driven wireless deep brain
stimulation (DBS) using magnetic nanostructures for therapeutic benefits in the mouse …
stimulation (DBS) using magnetic nanostructures for therapeutic benefits in the mouse …
Subthalamic neurons interact with nigral dopaminergic neurons to regulate movement in mice
JP Fan, X Zhang, Y Han, Y Ji, WX Gu, HC Wu… - Acta …, 2023 - Wiley Online Library
Aim This study aims to address the role of the interaction between subthalamic (STN)
neurons and substantia nigra pars compacta (SNc) dopaminergic (DA) neurons in …
neurons and substantia nigra pars compacta (SNc) dopaminergic (DA) neurons in …