[HTML][HTML] Kynurenine emerges from the shadows–Current knowledge on its fate and function
M Marszalek-Grabska, K Walczak, K Gawel… - Pharmacology & …, 2021 - Elsevier
Kynurenine (KYN), a main metabolite of tryptophan in mammals, is a direct precursor of
kynurenic acid, anthranilic acid and 3-hydroxykynurenine (3-HK). Under physiological …
kynurenic acid, anthranilic acid and 3-hydroxykynurenine (3-HK). Under physiological …
Implications of Kynurenine Pathway Metabolism for the Immune System, Hypothalamic–Pituitary–Adrenal Axis, and Neurotransmission in Alcohol Use Disorder
B Osuch, T Misztal, K Pałatyńska… - International Journal of …, 2024 - mdpi.com
In recent years, there has been a marked increase in interest in the role of the kynurenine
pathway (KP) in mechanisms associated with addictive behavior. Numerous reports …
pathway (KP) in mechanisms associated with addictive behavior. Numerous reports …
[HTML][HTML] Indoleamine-2, 3-dioxygenase mediates emotional deficits by the kynurenine/tryptophan pathway in the ethanol addiction/withdrawal mouse model
X Jiang, Q Lin, L Xu, Z Chen, Q Yan… - Frontiers in cellular …, 2020 - frontiersin.org
Objective Our study was designed to investigate whether the indoleamine-2, 3-dioxygenase
(IDO)-mediated kynurenine/tryptophan (KYN/TRP) pathway participates in the development …
(IDO)-mediated kynurenine/tryptophan (KYN/TRP) pathway participates in the development …
Direct implications between prenatal alcohol consumption and gut microbiome in the neurodevelopment of mice offspring–focusing on foetal alcoholic spectrum …
Disorders associated with substance abuse are a major public health crisis with few
treatment options. According to World Health Organization (WHO) ethanol is the most widely …
treatment options. According to World Health Organization (WHO) ethanol is the most widely …