Mucosal vaccines offer the potential to trigger robust protective immune responses at the
predominant sites of pathogen infection. In principle, the induction of adaptive immunity at …

Type 2 immunity is orchestrated by a canonical group of cytokines primarily produced by
innate lymphoid cells, group 2, and their adaptive counterparts, CD4+ helper type 2 cells …

Dietary fibres can exert beneficial anti-inflammatory effects through microbially fermented
short-chain fatty acid metabolites,, although the immunoregulatory roles of most fibre diets …

For over 35 years since Mosmann and Coffman proposed the seminal “type 1 T helper
(Th1)/type 2 T helper (Th2)” hypothesis in 1986, the immunological community has …

Group 2 innate lymphoid cells (ILC2s) reside in multiple tissues, including lymphoid organs
and barrier surfaces, and secrete type 2 cytokines including interleukin-5 (IL-5), IL-9, and IL …

Type I innate lymphoid cells (ILC1s) are critical regulators of inflammation and immunity in
mammalian tissues. However, their function in cancer is mostly undefined. Here, we show …

Background Although ample knowledge exists about phenotype and function of cutaneous T
lymphocytes, much less is known about the lymphocytic components of the skin's innate …

Group 2 innate lymphoid cells (ILC2s) represent innate homologs of type 2 helper T cells
(TH2) that participate in immune defense and tissue homeostasis through production of type …

Type 2 immune responses form a critical defence against enteric worm infections. In recent
years, mouse models have revealed shared and unique functions for group 2 innate …

Global microplastic (MP) contamination and the effects on the environment are well
described. However, the potential for MP consumption to affect human health remains …