An intricate interplay between genetic and environmental factors contributes to the
development of type 2 diabetes (T2D) and its complications. Therefore, it is not surprising …

Metabolic syndrome (MetS) is a multifaceted condition that increases the possibility of
developing atherosclerotic cardiovascular disease. MetS includes obesity, hypertension …

Cerebral stroke is a common neurological disease and often causes severe neurological
deficits. With high morbidity, mortality, and disability rates, stroke threatens patients' life …

Cardiovascular diseases (CVDs), a group of disorders affecting the heart or blood vessels,
are the primary cause of death worldwide, with an immense impact on patient quality of life …

MicroRNAs (miRs) regulate gene expression at the post-transcriptional level and are found
to be present in monocytes. This study aimed to investigate miR-221-5p, miR-21-5p, and …

Ischemia–reperfusion is a cascade of complex and interrelated pathological processes
underlying many human diseases, including such socially significant diseases as stroke …

Metformin has been used to treat cases of type 2 diabetes mellitus, and mounting studies
have shown that metformin can act alone or in synergy with other anticancer agents to …

Cardiovascular diseases (CVDs) and neurodegenerative disorders, such as diabetes
mellitus and Alzheimer's disease, share a common pathophysiological link involving insulin …

Metformin (MET) is a preferred drug for the treatment of type 2 diabetes mellitus. Recent
studies show that apart from its blood glucose‐lowering effects, it also inhibits the …

Fibrosis is the tissue scarring characterized by excess deposition of extracellular matrix
(ECM) proteins, mainly collagens. A fibrotic response can take place in any tissue of the …