Epidemiology of heart failure

A Groenewegen, FH Rutten, A Mosterd… - European journal of …, 2020 - Wiley Online Library
The heart failure syndrome has first been described as an emerging epidemic about 25
years ago. Today, because of a growing and ageing population, the total number of heart …

Heart failure: an underappreciated complication of diabetes. A consensus report of the American Diabetes Association

R Pop-Busui, JL Januzzi, D Bruemmer… - Diabetes …, 2022 - Am Diabetes Assoc
Heart failure (HF) has been recognized as a common complication of diabetes, with a
prevalence of up to 22% in individuals with diabetes and increasing incidence rates. Data …

Heart failure drug treatment

P Rossignol, AF Hernandez, SD Solomon, F Zannad - The Lancet, 2019 - thelancet.com
Heart failure is the most common cardiovascular reason for hospital admission for people
older than 60 years of age. Few areas in medicine have progressed as remarkably as heart …

Recent successes in heart failure treatment

CSP Lam, KF Docherty, JE Ho, JJV McMurray… - Nature Medicine, 2023 - nature.com
Remarkable recent advances have revolutionized the field of heart failure. Survival has
improved among individuals with heart failure and a reduced ejection fraction and for the …

Machine learning based on biomarker profiles identifies distinct subgroups of heart failure with preserved ejection fraction

RJ Woolley, D Ceelen, W Ouwerkerk… - European journal of …, 2021 - Wiley Online Library
Aims The lack of effective therapies for patients with heart failure with preserved ejection
fraction (HFpEF) is often ascribed to the heterogeneity of patients with HFpEF. We aimed to …

[HTML][HTML] Blood pressure and heart failure

GC Oh, HJ Cho - Clinical hypertension, 2020 - Springer
Background Hypertension is a leading cause of cardiovascular disease, stroke, and death. It
affects a substantial proportion of the population worldwide, and remains underdiagnosed …

The role of multimorbidity in patients with heart failure across the left ventricular ejection fraction spectrum: Data from the Swedish Heart Failure Registry

D Tomasoni, C Vitale, F Guidetti… - European Journal of …, 2024 - Wiley Online Library
Aims The aim of this analysis was to provide data on the overall comorbidity burden, both
cardiovascular (CV) and non‐CV, in a large real‐world heart failure (HF) population across …

How to manage heart failure with preserved ejection fraction: practical guidance for clinicians

AS Desai, CSP Lam, JJV McMurray, MM Redfield - Heart failure, 2023 - jacc.org
Although patients with heart failure with preserved ejection fraction (HFpEF)(left ventricular
ejection fraction≥ 50%) comprise nearly half of those with chronic heart failure, evidence …

Phenomapping in heart failure with preserved ejection fraction: insights, limitations, and future directions

AE Peters, J Tromp, SJ Shah, CSP Lam… - Cardiovascular …, 2022 - academic.oup.com
Heart failure with preserved ejection fraction (HFpEF) is a heterogeneous entity with
complex pathophysiology and manifestations. Phenomapping is the process of applying …

Allopurinol reduces oxidative stress and activates Nrf2/p62 to attenuate diabetic cardiomyopathy in rats

J Luo, D Yan, S Li, S Liu, F Zeng… - Journal of cellular …, 2020 - Wiley Online Library
Allopurinol (ALP) attenuates oxidative stress and diabetic cardiomyopathy (DCM), but the
mechanism is unclear. Activation of nuclear factor erythroid 2‐related factor 2 (Nrf2) …