Cerebral edema (CE) is a potentially devastating complication of diabetic ketoacidosis
(DKA) that almost exclusively occurs in children. Since its first description in 1936, numerous …

Abstract Purpose of Review Hyperglycemia in the emergency department (ED) is being
recognized as a public health problem and presents a clinical challenge. This review …

Diabetic ketoacidosis (DKA), a common onset modality of type 1 diabetes mellitus (T1DM),
can lead, in rare instances, to the development of cerebral edema, which is the leading …

Background Pediatric diabetic ketoacidosis (DKA) is a disease associated with several
complications that can be severe. One complication includes cerebral edema (CE), and …

Hyperglycaemic emergencies are associated with significant morbi-mortality and healthcare
costs. Management consists on fluid replacement, insulin therapy, and electrolyte correction …

We conducted a retrospective survey in pediatric centers belonging to the Italian Society for
Pediatric Diabetology and Endocrinology. The following data were collected for all new …

Abstract Treatment of paediatric diabetic ketoacidosis (DKA) includes careful attention to
fluids and electrolytes to minimize the risk of complications such as cerebral injury (CI) …

Diabetic ketoacidosis is a dynamic disease that requires regular reassessment of an
affected patient. Typical treatment regimens include crystalloid fluid therapy, insulin, and …

Background Children at high risk for developing type 1 diabetes (T1D) can be identified on
the basis of human leukocyte antigen (HLA) genotype and the subsequent development of …

Hypokalemia is common during the treatment of diabetic ketoacidosis (DKA); however,
severe hypokalemia at presentation prior to insulin treatment is exceedingly uncommon. A …