In vitro bioassays for detecting dioxin-like activity—Application potentials and limits of detection, a review

K Eichbaum, M Brinkmann, S Buchinger… - Science of the Total …, 2014 - Elsevier
Use of in vitro assays as screening tool to characterize contamination of a variety of
environmental matrices has become an increasingly popular and powerful toolbox in the …

Induction and suppression of cytochrome P450 1A by 3, 3′, 4, 4′, 5-pentachlorobiphenyl and its relationship to oxidative stress in the marine fish scup (Stenotomus …

JJ Schlezinger, JJ Stegeman - Aquatic toxicology, 2001 - Elsevier
The planar polychlorinated biphenyl (PCB) 3, 3′, 4, 4′-tetrachlorobiphenyl (TCB) causes
dose-dependent induction and post-transcriptional suppression of hepatic cytochrome P450 …

Combinatorial bio/chemical analysis of dioxin and dioxin-like compounds in waste recycling, feed/food, humans/wildlife and the environment

PA Behnisch, K Hosoe, S Sakai - Environment International, 2001 - Elsevier
The present review describes international activities using bioassays/biomarkers in
combination with chemical analysis to measure the effects of dioxin and dioxin-like …

In vitro EROD induction equivalency factors for the 10 PAHs generally monitored in risk assessment studies in The Netherlands

ATC Bosveld, PAF De Bie, NW Van den Brink… - Chemosphere, 2002 - Elsevier
The ethoxy resorufin dealkylase (EROD) inducing potency of 10 polycyclic aromatic
hydrocarbons (PAHs) is measured in the H4IIE in vitro bioassay and the results are …

Cytochrome P4501A induction potencies of polycyclic aromatic hydrocarbons in a fish hepatoma cell line: demonstration of additive interactions

K Fent, R Bätscher - Environmental Toxicology and Chemistry …, 2000 - Wiley Online Library
The relative CYP1A induction potencies, determined as ethoxyresorufin‐O‐deethylase
(EROD) activity, and the cytotoxicities of 19 compounds with one to six benzene rings …

Review of the effects of endocrine-disrupting chemicals in birds

JP Giesy, LA Feyk, PD Jones, K Kannan… - Pure and Applied …, 2003 - degruyter.com
There have been several case studies of the impact of chemical contaminants on birds at the
level of individuals or populations. While many of the chemicals involved in these incidents …

Biomarkers and bioassays for detecting dioxin-like compounds in the marine environment

ME Hahn - Science of the Total Environment, 2002 - Elsevier
The presence of toxic chemical contaminants in some marine organisms, including those
consumed by humans, is well known. Monitoring the levels of such contaminants and their …

Dioxins, dibenzofurans, PCBs and colonial, fish-eating water birds

JP Giesy, JP Ludwig, DE Tillitt - Dioxins and health, 1994 - Springer
Historically, the colonial, fish-eating water birds of the Great Lakes have been exposed to a
number of toxic, synthetic, halogenated compounds. 1-10 These exposures have resulted in …

Deformities, PCBs, and TCDD-equivalents in Double-crested Cormorants (Phalacrocorax auritus) and Caspian Terns (Hydroprogne caspia) of the upper Great Lakes …

JP Ludwig, H Kurita-Matsuba, HJ Auman… - Journal of Great Lakes …, 1996 - Elsevier
Deformities have been reported in many species of colonial waterbirds from several
localities on the Laurentian Great Lakes. The hypothesis that deformities were caused by …

[HTML][HTML] Bioanalytical tools: half a century of application for potable reuse

FDL Leusch, SA Snyder - Environmental Science: Water Research & …, 2015 - pubs.rsc.org
In vitro bioassays, more recently referred to as “bioanalytical tools” in an attempt to
emphasize their analytical purpose rather than the uncertain relation to adverse health …