The controversial role of human gut lachnospiraceae

M Vacca, G Celano, FM Calabrese, P Portincasa… - Microorganisms, 2020 - mdpi.com
The complex polymicrobial composition of human gut microbiota plays a key role in health
and disease. Lachnospiraceae belong to the core of gut microbiota, colonizing the intestinal …

Intestinal barrier and permeability in health, obesity and NAFLD

P Portincasa, L Bonfrate, M Khalil, MD Angelis… - Biomedicines, 2021 - mdpi.com
The largest surface of the human body exposed to the external environment is the gut. At this
level, the intestinal barrier includes luminal microbes, the mucin layer, gastrointestinal …

Liver steatosis, gut-liver axis, microbiome and environmental factors. A never-ending bidirectional cross-talk

A Di Ciaula, J Baj, G Garruti, G Celano… - Journal of clinical …, 2020 - mdpi.com
The prevalence of non-alcoholic fatty liver disease (NAFLD) is increasing worldwide and
parallels comorbidities such as obesity, metabolic syndrome, dyslipidemia, and diabetes …

Nonalcoholic fatty liver disease (NAFLD). Mitochondria as players and targets of therapies?

A Di Ciaula, S Passarella, H Shanmugam… - International Journal of …, 2021 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease and
represents the hepatic expression of several metabolic abnormalities of high epidemiologic …

COVID‐19 and non‐alcoholic fatty liver disease: two intersecting pandemics

P Portincasa, M Krawczyk, W Smyk… - European journal of …, 2020 - Wiley Online Library
Abstract Background Initial evidence from China suggests that most vulnerable subjects to
COVID‐19 infection suffer from pre‐existing illness, including metabolic abnormalities. The …

Hepatic consequences of COVID-19 infection. Lapping or biting?

P Portincasa, M Krawczyk, A Machill, F Lammert… - European journal of …, 2020 - Elsevier
The outbreak of coronavirus disease 2019 (COVID-19) starting last December in China
placed emphasis on liver involvement during infection. This review discusses the underlying …

NAFLD: genetics and its clinical implications

D Sharma, P Mandal - Clinics and Research in Hepatology and …, 2022 - Elsevier
Worldwide non-alcoholic fatty liver disease (NAFLD) is recognized as the most common type
of liver disease and its burden increasing at an alarming rate. NAFLD entails steatosis …

Metabolic syndrome: a narrative review from the oxidative stress to the management of related diseases

G Martemucci, G Fracchiolla, M Muraglia, R Tardugno… - Antioxidants, 2023 - mdpi.com
Metabolic syndrome (MS) is a growing disorder affecting thousands of people worldwide,
especially in industrialised countries, increasing mortality. Oxidative stress, hyperglycaemia …

The role of microbiota in nonalcoholic fatty liver disease

A Di Ciaula, L Bonfrate… - European Journal of …, 2022 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) is the most frequent liver disease worldwide. Gut
microbiota can play a role in the pathogenesis of NAFLD since dysbiosis is associated with …

NAFLD, MAFLD, and beyond: one or several acronyms for better comprehension and patient care

P Portincasa - Internal and Emergency Medicine, 2023 - Springer
The term non-alcoholic fatty liver disease (NAFLD) has rapidly become the most common
type of chronic liver disease. NAFLD points to excessive hepatic fat storage and no evidence …