Synthetic glycans to improve current glycoconjugate vaccines and fight antimicrobial resistance

L Del Bino, KE Østerlid, DY Wu, F Nonne… - Chemical …, 2022 - ACS Publications
Antimicrobial resistance (AMR) is emerging as the next potential pandemic. Different
microorganisms, including the bacteria Acinetobacter baumannii, Clostridioides difficile …

[HTML][HTML] Antimicrobial resistant strains of Salmonella typhi: The role of illicit antibiotics sales, misuse, and self-medication practices in Pakistan

OA Shaikh, Z Asghar, RM Aftab, S Amin… - Journal of Infection and …, 2023 - Elsevier
Typhoid fever, caused by the bacterium Salmonella typhi, is an often-fatal illness prevalent
in Africa and South Asia. The illness has seen an alarming rise in multi-drug-resistant (MDR) …

Targeting a highly conserved domain in bacterial histidine kinases to generate inhibitors with broad spectrum activity

CA Fihn, EE Carlson - Current opinion in microbiology, 2021 - Elsevier
Highlights•CA domain of bacterial HKs presents a novel anti-virulence or antibiotic
target.•CA domain targeted molecules can inhibit multiple HKs, increasing effectiveness.• …

[PDF][PDF] Epidemiology of typhoid fever in Balad City, Iraq

AR Medhat, AAJ Aljanabay - International Journal of Health …, 2022 - academia.edu
One thousand nine hundred and twenty individuals admitted to the general teaching
hospital in Balad City, suffer from abdominal pain, fever, a headache and nausea. Acute and …

[HTML][HTML] Redefining serological diagnostics with immunoaffinity proteomics

J Walter, Z Eludin, AP Drabovich - Clinical Proteomics, 2023 - Springer
Serological diagnostics is generally defined as the detection of specific human
immunoglobulins developed against viral, bacterial, or parasitic diseases. Serological tests …

Prioritization of potential vaccine candidates and designing a multiepitope-based subunit vaccine against multidrug-resistant Salmonella Typhi str. CT18: A subtractive …

Y Chand, S Singh - Microbial Pathogenesis, 2021 - Elsevier
Salmonella enterica serovar Typhi (S. Typhi), a causative agent of typhoid fever, is a Gram-
negative, human-restricted pathogen that causes significant morbidity and mortality …

Defying the odds: Determinants of the antimicrobial response of Salmonella Typhi and their interplay

AR Chowdhury, D Mukherjee… - Molecular …, 2024 - Wiley Online Library
Salmonella Typhi, the invasive serovar of S. enterica subspecies enterica, causes typhoid
fever in healthy human hosts. The emergence of antibiotic‐resistant strains has consistently …

[HTML][HTML] Understanding the Mechanism of Antimicrobial Resistance and Pathogenesis of Salmonella enterica Serovar Typhi

M Khan, S Shamim - Microorganisms, 2022 - mdpi.com
Salmonella enterica serovar Typhi (S. Typhi) is a Gram-negative pathogen that causes
typhoid fever in humans. Though many serotypes of Salmonella spp. are capable of causing …

[PDF][PDF] Kajian literatur: profil resistensi salmonella typhi dan pemilihan antibiotik pada demam tifoid

DA Sanjaya, H Meriyani, RRA Juanita, N Budiartha - J Pharm Sci, 2022 - academia.edu
Demam tifoid merupakan penyakit infeksi yang disebabkan oleh bakteri Gramnegatif yaitu
Salmonella typhi. Munculnya multidrug-resistant Salmonella typhi (MDRST) dan extensively …

Safety and immunogenicity of Vi-diphtheria toxoid typhoid conjugate vaccine among children below 2 years: a systematic review and meta-analysis

A Mohamed Taha, K Abouelmagd… - Frontiers in …, 2024 - frontiersin.org
Background The Vi-diphtheria toxoid typhoid conjugate vaccine (Vi-DT) has shown
promising results in preventing typhoid fever in children under 2 years of age. However, a …