Epidemiology of lung cancer: Diagnosis and management of lung cancer: American College of Chest Physicians evidence-based clinical practice guidelines

AJ Alberg, MV Brock, JG Ford, JM Samet, SD Spivack - Chest, 2013 - Elsevier
Background Ever since a lung cancer epidemic emerged in the mid-1900s, the
epidemiology of lung cancer has been intensively investigated to characterize its causes …

Liquid biopsies based on DNA methylation as biomarkers for the detection and prognosis of lung cancer

P Li, S Liu, L Du, G Mohseni, Y Zhang, C Wang - Clinical epigenetics, 2022 - Springer
Lung cancer (LC) is the main cause of cancer-related mortality. Most LC patients are
diagnosed in an advanced stage when the symptoms are obvious, and the prognosis is …

Lung cancer epigenetics: from knowledge to applications

M Duruisseaux, M Esteller - Seminars in cancer biology, 2018 - Elsevier
Lung cancer is the leading cause of cancer-related mortality worldwide. Advances in our
understanding of the genomics of lung cancer have led to substantial progress in the …

DNA methylation-based testing in liquid biopsies as detection and prognostic biomarkers for the four major cancer types

V Constâncio, SP Nunes, R Henrique, C Jerónimo - Cells, 2020 - mdpi.com
Lung, breast, colorectal, and prostate cancers are the most incident worldwide. Optimal
population-based cancer screening methods remain an unmet need, since cancer detection …

Droplet-based digital PCR and next generation sequencing for monitoring circulating tumor DNA: a cancer diagnostic perspective

M Postel, A Roosen, P Laurent-Puig… - Expert review of …, 2018 - Taylor & Francis
Introduction: Early detection of cancers through the analysis of ctDNA could have a
significant impact on morbidity and mortality of cancer patients. However, using ctDNA for …

Environmental chemical exposures and human epigenetics

L Hou, X Zhang, D Wang… - International journal of …, 2012 - academic.oup.com
Every year more than 13 million deaths worldwide are due to environmental pollutants, and
approximately 24% of diseases are caused by environmental exposures that might be …

[HTML][HTML] HIF-1ɑ-regulated miR-1275 maintains stem cell-like phenotypes and promotes the progression of LUAD by simultaneously activating Wnt/β-catenin and …

N Jiang, C Zou, Y Zhu, Y Luo, L Chen, Y Lei, K Tang… - Theranostics, 2020 - ncbi.nlm.nih.gov
Abstract Rationale: Cancer stem cells (CSCs) are considered to be essential for
tumorigenesis, recurrence, and metastasis and therefore serve as a biomarker for tumor …

Diagnostic and prognostic epigenetic biomarkers in cancer

P Costa-Pinheiro, D Montezuma, R Henrique… - …, 2015 - Taylor & Francis
Growing cancer incidence and mortality worldwide demands development of accurate
biomarkers to perfect detection, diagnosis, prognostication and monitoring. Urologic …

The role of liquid biopsy in early diagnosis of lung cancer

C Freitas, C Sousa, F Machado, M Serino… - Frontiers in …, 2021 - frontiersin.org
Liquid biopsy is an emerging technology with a potential role in the screening and early
detection of lung cancer. Several liquid biopsy-derived biomarkers have been identified and …

Challenges and opportunities of cfDNA analysis implementation in clinical practice: Perspective of the International Society of Liquid Biopsy (ISLB)

C Rolfo, AF Cardona, M Cristofanilli, L Paz-Ares… - Critical Reviews in …, 2020 - Elsevier
Precision medicine was born with the development of new diagnostic techniques and
targeted drugs, yielding better outcomes in cancer care. With the evolution and increasing …