Understanding the Immunopathology of HTLV-1-Associated Adult T-Cell Leukemia/Lymphoma: A Comprehensive Review

S Nakahata, D Enriquez-Vera, MI Jahan, K Sugata… - Biomolecules, 2023 - mdpi.com
Human T-cell leukemia virus type-1 (HTLV-1) causes adult T-cell leukemia/lymphoma (ATL).
HTLV-1 carriers have a lifelong asymptomatic balance between infected cells and host …

Retroviral b‐Zip protein (HBZ) contributes to the release of soluble and exosomal immune checkpoint molecules in the context of neuroinflammation

J Joseph, TA Premeaux, DO Pinto… - Journal of …, 2023 - Wiley Online Library
HTLV‐I‐associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a chronic,
progressive, neuroinflammatory demyelinating condition of the spinal cord. We have …

The novel link between gene expression profiles of adult T-cell leukemia/lymphoma patients' Peripheral blood lymphocytes and ferroptosis susceptibility

Y Wang, H Iha - Genes, 2023 - mdpi.com
Ferroptosis, a regulated cell death dependent on iron, has garnered attention as a potential
broad-spectrum anticancer approach in leukemia research. However, there has been limited …

Reprogramming of pyrimidine nucleotide metabolism supports vigorous cell proliferation of normal and malignant T cells

T Watanabe, Y Yamamoto, Y Kurahashi… - Blood …, 2024 - ashpublications.org
Adult T-cell leukemia/lymphoma (ATL) is triggered by infection with human T-cell
lymphotropic virus-1 (HTLV-1). Here, we describe the reprogramming of pyrimidine …

[HTML][HTML] IMiD/CELMoD-induced growth suppression of adult T-cell leukemia/lymphoma cells via cereblon through downregulation of target proteins and their …

Y Wang, S Shimosaki, E Ikebe, H Iha… - Frontiers in …, 2024 - frontiersin.org
Adult T-cell leukemia/lymphoma (ATL) is an aggressive T-cell neoplasia associated with
human T-cell leukemia virus type 1 (HTLV-1) infection and has an extremely poor prognosis …

[HTML][HTML] Basic zipper protein (HBZ): biomarcador diagnóstico y de seguimiento de leucemia/linfoma T del adulto

V Riaño Ibáñez, DA Villamil Rodríguez… - Revista Cubana de …, 2023 - scielo.sld.cu
Objetivo: Presentar la proteína basic zipper protein como marcador diagnóstico y de
seguimiento al tratamiento de la leucemia-linfoma de células T. Métodos: Se consultó …

Evaluation of ALKBH2 gene expression in patients with adult T-cell leukemia

Y Wada, T Naito, H Ushirogawa, A Hatamoto… - 2023 - researchsquare.com
Background Human T-cell leukemia virus type 1 (HTLV-1) is an oncogenic virus that causes
adult T-cell leukemia (ATL). Patients infected with HTLV-1 are considered HTLV-1 carriers …

Impact sur la relation hôte-pathogène de l'interaction entre l'hélicase UPF1 et les transporteurs rétroviraux, Rex d'HTLV-1 et Rev d'HIV-1

L Prochasson - 2022 - theses.hal.science
De par son rôle central dans plusieurs voies de dégradation de l'ARN, l'hélicase UPF1 (UP-
Frameshift 1) est associée à différents processus cellulaires contrôlant la stabilité de l'ARN …