[HTML][HTML] FSP1: a key regulator of ferroptosis

W Li, L Liang, S Liu, H Yi, Y Zhou - Trends in Molecular Medicine, 2023 - cell.com
Abstract Ferroptosis suppressor protein 1 (FSP1) is one of the main regulatory molecules of
ferroptosis. FSP1 functions through the FSP1-coenzyme Q10 (CoQ10)-NAD (P) H axis and …

Ferroptosis in Parkinson's disease: Molecular mechanisms and therapeutic potential

X Ding, L Gao, Z Han, S Eleuteri, W Shi, Y Shen… - Ageing research …, 2023 - Elsevier
Parkinson's Disease (PD) is characterized by the progressive loss of dopaminergic neurons
in the substantia nigra (SN), leading to motor and non-motor symptoms. While the exact …

[HTML][HTML] Microbiota–gut–brain axis and its therapeutic applications in neurodegenerative diseases

JS Loh, WQ Mak, LKS Tan, CX Ng, HH Chan… - … and Targeted Therapy, 2024 - nature.com
The human gastrointestinal tract is populated with a diverse microbial community. The vast
genetic and metabolic potential of the gut microbiome underpins its ubiquity in nearly every …

The influence of microbiota on ferroptosis in intestinal diseases

T Yao, L Li - Gut Microbes, 2023 - Taylor & Francis
Ferroptosis is a distinctive form of iron-dependent necrotic cell death, characterized by
excessive lipid peroxidation on cellular membranes and compromised cellular antioxidant …

Gut microbiota bridges the iron homeostasis and host health

L Xiao, R Tang, J Wang, D Wan, Y Yin, L Xie - Science China Life …, 2023 - Springer
The gut microbiota acts as a symbiotic microecosystem that plays an indispensable role in
the regulation of a number of metabolic processes in the host by secreting secondary …

[HTML][HTML] Iron toxicity, ferroptosis and microbiota in Parkinson's disease: Implications for novel targets

FV Carvalho, HE Landis, B Getachew… - Advances in …, 2024 - ncbi.nlm.nih.gov
Parkinson's Disease (PD) is a progressive neurodegenerative disease characterized by loss
of dopaminergic neurons in substantia nigra pars compacta (SNpc). Iron (Fe)-dependent …

[HTML][HTML] Salidroside Mediated the Nrf2/GPX4 Pathway to Attenuates Ferroptosis in Parkinson's Disease

J Shen, S Chen, X Li, L Wu, X Mao, J Jiang… - Neurochemical …, 2024 - Springer
Parkinson's Disease (PD) is characterized by the loss of dopaminergic neurons, with
ferroptosis playing a significant role. Salidroside (SAL) has shown neuroprotective potential …

[HTML][HTML] The role of cellular defense systems of ferroptosis in Parkinson's disease and Alzheimer's disease

J Chu, J Li, L Sun, J Wei - International Journal of Molecular Sciences, 2023 - mdpi.com
Parkinson's disease (PD) and Alzheimer's disease (AD) are the most common rapidly
developing neurodegenerative diseases that lead to serious health and socio-economic …

[HTML][HTML] The Role of Calcium and Iron Homeostasis in Parkinson's Disease

J Wang, J Zhao, K Zhao, S Wu, X Chen, W Hu - Brain Sciences, 2024 - mdpi.com
Calcium and iron are essential elements that regulate many important processes of
eukaryotic cells. Failure to maintain homeostasis of calcium and iron causes cell dysfunction …

Mapping the Research of Ferroptosis in Parkinson's Disease from 2013 to 2023: A Scientometric Review

Y Chen, Z Wu, S Li, Q Chen, L Wang, X Qi… - Drug Design …, 2024 - Taylor & Francis
Methods Related studies on PD and ferroptosis were searched in Web of Science Core
Collection (WOSCC) from inception to 2023. VOSviewer, CiteSpace, RStudio, and Scimago …