Fractionating ambient humic-like substances (HULIS) for their reactive oxygen species activity–Assessing the importance of quinones and atmospheric aging

V Verma, Y Wang, R El-Afifi, T Fang, J Rowland… - Atmospheric …, 2015 - Elsevier
In this paper, we present a technique to identify the redox-active components of fine organic
aerosols by fractionating humic-like substances (HULIS). We applied this technique to a …

HULIS enhancement of hydroxyl radical formation from Fe (II): Kinetics of fulvic acid–Fe (II) complexes in the presence of lung antioxidants

DH Gonzalez, CK Cala, Q Peng… - Environmental science & …, 2017 - ACS Publications
Oxidative stress mediated by reactive oxygen species (ROS) is a hypothesized mechanism
for particulate-matter related health effects. Fe (II) is a key player in ROS formation in …

Associations between three specific a-cellular measures of the oxidative potential of particulate matter and markers of acute airway and nasal inflammation in healthy …

NAH Janssen, M Strak, A Yang, B Hellack… - Occupational and …, 2015 - oem.bmj.com
Introduction We evaluated associations between three a-cellular measures of the oxidative
potential (OP) of particulate matter (PM) and acute health effects. Methods We exposed 31 …

Oxidative potential of semi-volatile and non volatile particulate matter (PM) from heavy-duty vehicles retrofitted with emission control technologies

S Biswas, V Verma, JJ Schauer… - Environmental …, 2009 - ACS Publications
Advanced exhaust after-treatment devices for diesel vehicles are less effective in controlling
semivolatile species than the refractory PM fractions. This study investigates the oxidative …

In vitro cytotoxicity of silver nanoparticles and zinc oxide nanoparticles to human epithelial colorectal adenocarcinoma (Caco-2) cells

Y Song, R Guan, F Lyu, T Kang, Y Wu… - … and Molecular Mechanisms …, 2014 - Elsevier
With the increasing applications of silver nanoparticles (Ag NPs) and zinc oxide
nanoparticles (ZnO NPs) in foods and cosmetics, the concerns about the potential toxicities …

An apportionment method for the oxidative potential of atmospheric particulate matter sources: application to a one-year study in Chamonix, France

S Weber, G Uzu, A Calas, F Chevrier… - Atmospheric …, 2018 - acp.copernicus.org
Inhaled aerosolized particulate matter (PM) induces cellular oxidative stress in vivo, leading
to adverse health outcomes. The oxidative potential (OP) of PM appears to be a more …

An integrated approach to testing and assessment to support grouping and read-across of nanomaterials after inhalation exposure

HM Braakhuis, F Murphy, L Ma-Hock… - Applied In Vitro …, 2021 - liebertpub.com
Introduction: Here, we describe the generation of hypotheses for grouping nanoforms (NFs)
after inhalation exposure and the tailored Integrated Approaches to Testing and Assessment …

Ambient particulate matter activates the aryl hydrocarbon receptor in dendritic cells and enhances Th17 polarization

AR Castañeda, KE Pinkerton, KJ Bein… - Toxicology letters, 2018 - Elsevier
The objective of this study was to explore the role of the aryl hydrocarbon receptor (AhR) in
ambient particulate matter (PM)-mediated activation of dendritic cells (DCs) and Th17 …

Fine particulate air pollution and adverse birth outcomes: effect modification by regional nonvolatile oxidative potential

E Lavigne, RT Burnett, DM Stieb… - Environmental …, 2018 - ehp.niehs.nih.gov
Background: Prenatal exposure to fine particulate matter air pollution with aerodynamic
diameter≤ 2.5 μ m (PM 2.5) has been associated with preterm delivery and low birth weight …

Nanoparticles, lung injury, and the role of oxidant stress

AK Madl, LE Plummer, C Carosino… - Annual review of …, 2014 - annualreviews.org
The emergence of engineered nanoscale materials has provided significant advancements
in electronic, biomedical, and material science applications. Both engineered nanoparticles …