[HTML][HTML] Addiction of cancer stem cells to MUC1-C in triple-negative breast cancer progression

N Yamashita, D Kufe - International Journal of Molecular Sciences, 2022 - mdpi.com
Triple-negative breast cancer (TNBC) is an aggressive malignancy with limited treatment
options. TNBC progression is associated with expansion of cancer stem cells (CSCs). Few …

[HTML][HTML] Combined atezolizumab and nab-paclitaxel in the treatment of triple negative breast cancer: a meta-analysis on their efficacy and safety

K Sharmni Vishnu, TT Win, SN Aye, AK Basavaraj - BMC cancer, 2022 - Springer
Background Triple negative breast cancer (TNBC) is clinically aggressive breast cancer with
a poor prognosis. Approximately 20% of TNBC has been found to express programmed …

[HTML][HTML] Understanding and harnessing triple-negative breast cancer-related microbiota in oncology

C Devoy, Y Flores Bueso, M Tangney - Frontiers in Oncology, 2022 - frontiersin.org
Bacterial inhabitants of the body have the potential to play a role in various stages of cancer
initiation, progression, and treatment. These bacteria may be distal to the primary tumour …

[HTML][HTML] MicroRNAs with multiple targets of immune checkpoints, as a potential sensitizer for immune checkpoint inhibitors in breast cancer treatment

H Zhou, W Jia, L Lu, R Han - Cancers, 2023 - mdpi.com
Simple Summary Based on the latest research progresses, application of immune
checkpoint inhibitors (ICIs) has shown promise in treating breast cancer. Moreover, novel …

[HTML][HTML] ASAH1 facilitates TNBC by DUSP5 suppression-driven activation of MAP kinase pathway and represents a therapeutic vulnerability

KK Reddi, S Chava, SC Chabattula, YJK Edwards… - Cell Death & …, 2024 - nature.com
Triple-negative breast cancer (TNBC) is a subtype of breast cancer that is prone to
metastasis and therapy resistance. Owing to its aggressive nature and limited availability of …

Targeting receptor tyrosine kinases as a novel strategy for the treatment of triple-negative breast cancer

SK Jaradat, NM Ayoub, AH Al Sharie… - Technology in Cancer …, 2024 - journals.sagepub.com
Triple-negative breast cancer (TNBC) comprises a group of aggressive and heterogeneous
breast carcinoma. Chemotherapy is the mainstay for the treatment of triple-negative tumors …

Exploring the human microbiome–A step forward for precision medicine in breast cancer

A Jotshi, KK Sukla, MM Haque, C Bose… - Cancer …, 2023 - Wiley Online Library
Background The second most frequent cancer in the world and the most common
malignancy in women is breast cancer. Breast cancer is a significant health concern in India …

[HTML][HTML] Dysregulation of systemic soluble immune checkpoints in early breast cancer is attenuated following administration of neoadjuvant chemotherapy and is …

BL Rapoport, HC Steel, CA Benn, S Nayler… - Frontiers in …, 2023 - frontiersin.org
Neoadjuvant chemotherapy (NAC) may alter the immune landscape of patients with early
breast cancer (BC), potentially setting the scene for more effective implementation of …

Shortwave‐Infrared‐Emitting Nanoprobes for CD8 Targeting and In Vivo Imaging of Cytotoxic T Cells in Breast Cancer

JV Shah, JN Siebert, X Zhao, S He… - Advanced …, 2024 - Wiley Online Library
Checkpoint immunotherapy has made great strides in the treatment of solid tumors, but
many patients do not respond to immune checkpoint inhibitors. Identification of tumor …

GLORIA: phase III, open-label study of adagloxad simolenin/OBI-821 in patients with high-risk triple-negative breast cancer

HS Rugo, J Cortes, CH Barrios, P Cabrera, B Xu… - Future …, 2022 - Taylor & Francis
Triple-negative breast cancer (TNBC) has the highest rate of distant metastasis and poorest
overall survival among breast cancer subtypes. In a phase II study, adagloxad simolenin …