[HTML][HTML] Addiction of cancer stem cells to MUC1-C in triple-negative breast cancer progression
N Yamashita, D Kufe - International Journal of Molecular Sciences, 2022 - mdpi.com
Triple-negative breast cancer (TNBC) is an aggressive malignancy with limited treatment
options. TNBC progression is associated with expansion of cancer stem cells (CSCs). Few …
options. TNBC progression is associated with expansion of cancer stem cells (CSCs). Few …
[HTML][HTML] Combined atezolizumab and nab-paclitaxel in the treatment of triple negative breast cancer: a meta-analysis on their efficacy and safety
Background Triple negative breast cancer (TNBC) is clinically aggressive breast cancer with
a poor prognosis. Approximately 20% of TNBC has been found to express programmed …
a poor prognosis. Approximately 20% of TNBC has been found to express programmed …
[HTML][HTML] Understanding and harnessing triple-negative breast cancer-related microbiota in oncology
C Devoy, Y Flores Bueso, M Tangney - Frontiers in Oncology, 2022 - frontiersin.org
Bacterial inhabitants of the body have the potential to play a role in various stages of cancer
initiation, progression, and treatment. These bacteria may be distal to the primary tumour …
initiation, progression, and treatment. These bacteria may be distal to the primary tumour …
[HTML][HTML] MicroRNAs with multiple targets of immune checkpoints, as a potential sensitizer for immune checkpoint inhibitors in breast cancer treatment
H Zhou, W Jia, L Lu, R Han - Cancers, 2023 - mdpi.com
Simple Summary Based on the latest research progresses, application of immune
checkpoint inhibitors (ICIs) has shown promise in treating breast cancer. Moreover, novel …
checkpoint inhibitors (ICIs) has shown promise in treating breast cancer. Moreover, novel …
[HTML][HTML] ASAH1 facilitates TNBC by DUSP5 suppression-driven activation of MAP kinase pathway and represents a therapeutic vulnerability
Triple-negative breast cancer (TNBC) is a subtype of breast cancer that is prone to
metastasis and therapy resistance. Owing to its aggressive nature and limited availability of …
metastasis and therapy resistance. Owing to its aggressive nature and limited availability of …
Targeting receptor tyrosine kinases as a novel strategy for the treatment of triple-negative breast cancer
SK Jaradat, NM Ayoub, AH Al Sharie… - Technology in Cancer …, 2024 - journals.sagepub.com
Triple-negative breast cancer (TNBC) comprises a group of aggressive and heterogeneous
breast carcinoma. Chemotherapy is the mainstay for the treatment of triple-negative tumors …
breast carcinoma. Chemotherapy is the mainstay for the treatment of triple-negative tumors …
Exploring the human microbiome–A step forward for precision medicine in breast cancer
Background The second most frequent cancer in the world and the most common
malignancy in women is breast cancer. Breast cancer is a significant health concern in India …
malignancy in women is breast cancer. Breast cancer is a significant health concern in India …
[HTML][HTML] Dysregulation of systemic soluble immune checkpoints in early breast cancer is attenuated following administration of neoadjuvant chemotherapy and is …
BL Rapoport, HC Steel, CA Benn, S Nayler… - Frontiers in …, 2023 - frontiersin.org
Neoadjuvant chemotherapy (NAC) may alter the immune landscape of patients with early
breast cancer (BC), potentially setting the scene for more effective implementation of …
breast cancer (BC), potentially setting the scene for more effective implementation of …
Shortwave‐Infrared‐Emitting Nanoprobes for CD8 Targeting and In Vivo Imaging of Cytotoxic T Cells in Breast Cancer
Checkpoint immunotherapy has made great strides in the treatment of solid tumors, but
many patients do not respond to immune checkpoint inhibitors. Identification of tumor …
many patients do not respond to immune checkpoint inhibitors. Identification of tumor …
GLORIA: phase III, open-label study of adagloxad simolenin/OBI-821 in patients with high-risk triple-negative breast cancer
Triple-negative breast cancer (TNBC) has the highest rate of distant metastasis and poorest
overall survival among breast cancer subtypes. In a phase II study, adagloxad simolenin …
overall survival among breast cancer subtypes. In a phase II study, adagloxad simolenin …