[HTML][HTML] Gut microbiota: an important player in type 2 diabetes mellitus

Z Zhou, B Sun, D Yu, C Zhu - Frontiers in cellular and infection …, 2022 - frontiersin.org
Type 2 diabetes mellitus (T2DM) is one of the common metabolic diseases in the world. Due
to the rise in morbidity and mortality, it has become a global health problem. To date, T2DM …

Butyrate in energy metabolism: there is still more to learn

L Zhang, C Liu, Q Jiang, Y Yin - Trends in Endocrinology & Metabolism, 2021 - cell.com
Butyrate, a main product of gut microbial fermentation, has been recognized as an important
mediator of gut microbiota regulation in whole body energy homeostasis. However, the …

Butyrate to combat obesity and obesity‐associated metabolic disorders: current status and future implications for therapeutic use

T van Deuren, EE Blaak, EE Canfora - Obesity Reviews, 2022 - Wiley Online Library
Evidence is increasing that disturbances in the gut microbiome may play a significant role in
the etiology of obesity and type 2 diabetes. The short chain fatty acid butyrate, a major end …

Butyrate ameliorates skeletal muscle atrophy in diabetic nephropathy by enhancing gut barrier function and FFA2‐mediated PI3K/Akt/mTOR signals

G Tang, Y Du, H Guan, J Jia, N Zhu… - British Journal of …, 2022 - Wiley Online Library
Background and Purpose Muscle protein catabolism in patients with diabetic nephropathy
(DN) results in striking loss of muscle proteins, which increases morbidity and mortality risks …

Gut microbiome and its impact on obesity and obesity-related disorders

S Sankararaman, K Noriega, S Velayuthan… - Current …, 2023 - Springer
Abstract Purpose of Review The prevalence of overweight and obesity has been increasing
worldwide at an alarming rate. Gut microbiota intimately influence host energy metabolism …

Modulation of short‐chain fatty acids as potential therapy method for type 2 diabetes mellitus

R Tang, L Li - Canadian Journal of Infectious Diseases and …, 2021 - Wiley Online Library
In recent years, the relationship between intestinal microbiota (IM) and the pathogenesis of
type 2 diabetes mellitus (T2DM) has attracted much attention. The beneficial effects of IM on …

The antidiabetic effects of Bifidobacterium longum subsp. longum BL21 through regulating gut microbiota structure in type 2 diabetic mice

J Hao, Y Zhang, T Wu, R Liu, W Sui, J Zhu, S Fang… - Food & Function, 2022 - pubs.rsc.org
Bifidobacterium longum subsp. longum BL21 (BL21) possesses hypoglycemic activity, but
its anti-diabetic mechanism has rarely been illustrated. In the present work, the effects of …

Effectiveness of human-origin Lactobacillus plantarum PL-02 in improving muscle mass, exercise performance and anti-fatigue

MC Lee, YJ Hsu, HH Ho, YW Kuo, WY Lin, SY Tsai… - Scientific Reports, 2021 - nature.com
Gut microbiota is very important for energy metabolism and regulation, which in turn affect
the health and physiological functions of the host, and provide energy required for exercise …

Amelioration of non-alcoholic fatty liver disease by sodium butyrate is linked to the modulation of intestinal tight junctions in db/db mice

T Yang, H Yang, C Heng, H Wang, S Chen, Y Hu… - Food & function, 2020 - pubs.rsc.org
The intestinal microenvironment, a potential factor that contributes to the development of non-
alcoholic fatty liver disease (NALFD) and type 2 diabetes (T2DM), has a close relationship …

Epigenetic modifications in pancreas development, diabetes, and therapeutics

S Kaimala, CA Kumar, MZ Allouh… - Medicinal Research …, 2022 - Wiley Online Library
Abstract A recent International Diabetes Federation report suggests that more than 463
million people between 20 and 79 years have diabetes. Of the 20 million women affected by …