Aging and cancer are the most important issues to research. The population in the world is
growing older, and the incidence of cancer increases with age. There is no doubt about the …

Nitric oxide (NO) works as a retrograde neurotransmitter in synapses, allows the brain blood
flow and also has important roles in intracellular signaling in neurons from the regulation of …

In recent years there has been enormous interest in researching oxidative stress. Reactive
oxygen species (ROS) are derived from the metabolism of oxygen as by-products of cell …

Redox-dependent processes influence most cellular functions, such as differentiation,
proliferation, and apoptosis. Mitochondria are at the center of these processes, as …

This review concentrates on advances in nitric oxide synthase (NOS) structure, function and
inhibition made in the last seven years, during which time substantial advances have been …

Arginine is one of the most versatile amino acids in animal cells, serving as a precursor for
the synthesis not only of proteins but also of nitric oxide, urea, polyamines, proline …

Mitochondrially generated reactive oxygen species are involved in a myriad of signaling and
damaging pathways in different tissues. In addition, mitochondria are an important target of …

Nitric oxide, nitric oxide derivatives and reactive oxygen intermediates are toxic molecules of
the immune system which contribute to the control of microbial pathogens and tumors. There …

Recently nitric oxide (NO) has emerged as a key signalling molecule in plants. Here we
review the potential sources of endogenous NO, outline the biological processes likely to be …

Nitric oxide (NO) is synthesized from l-arginine by NO synthase in virtually all cell types.
Emerging evidence shows that NO regulates the metabolism of glucose, fatty acids and …