[HTML][HTML] Equine asthma: current understanding and future directions

L Couetil, JM Cardwell, R Leguillette… - Frontiers in veterinary …, 2020 - frontiersin.org
The 2019 Havemeyer Workshop brought together researchers and clinicians to discuss the
latest information on Equine Asthma and provide future research directions. Current clinical …

[HTML][HTML] A comparative review of equine SIRS, sepsis, and neutrophils

MK Sheats - Frontiers in veterinary science, 2019 - frontiersin.org
The most recent definition of sepsis in human medicine can be summarized as organ
dysfunction caused by a dysregulated host response to infection. In equine medicine …

[HTML][HTML] The immune mechanisms of severe equine asthma—Current understanding and what is missing

J Simões, M Batista, P Tilley - Animals, 2022 - mdpi.com
Simple Summary Severe equine asthma (sEA) is a highly prevalent respiratory disease
affecting adult horses. Affected horses present with cough, nasal discharge and increased …

[HTML][HTML] Neutrophil extracellular traps are found in bronchoalveolar lavage fluids of horses with severe asthma and correlate with asthma severity

P Janssen, I Tosi, A Hego, P Maréchal… - Frontiers in …, 2022 - frontiersin.org
Asthma encompasses a spectrum of heterogenous immune-mediated respiratory disorders
sharing a similar clinical pattern characterized by cough, wheeze and exercise intolerance …

[HTML][HTML] Immunoproteomics reveal increased serum IgG3/5 binding to Dermatophagoides and yeast protein antigens in severe equine asthma in a preliminary study

CL Schnabel, MC Jentsch, S Lübke… - Frontiers in …, 2023 - frontiersin.org
Introduction Severe equine asthma (SEA) is a common, chronic respiratory disease of
horses characterized by hyperreactivity to hay dust which has many similarities to severe …

[HTML][HTML] Decision making in severe equine asthma—Diagnosis and monitoring

J Simões, P Tilley - Animals, 2023 - mdpi.com
Simple Summary Severe equine asthma (SEA) is an important respiratory disease affecting
a large number of horses worldwide. This chronic disease induces cough and respiratory …

[HTML][HTML] Role of cellular metabolism in the formation of neutrophil extracellular traps in airway diseases

G Moran, B Uberti, J Quiroga - Frontiers in Immunology, 2022 - frontiersin.org
Neutrophil extracellular traps (NETs) are a recently described mechanism of neutrophils that
play an important role in health and disease. NETs are an innate defense mechanism that …

Comparative review of asthma in farmers and horses

MK Sheats, KU Davis, JA Poole - Current allergy and asthma reports, 2019 - Springer
Abstract Purpose of Review Farmers are routinely exposed to organic dusts and
aeroallergens that can have adverse respiratory health effects including asthma. Horses are …

Equine bone marrow-derived mesenchymal stromal cells inhibit reactive oxygen species production by neutrophils

G Espinosa, A Plaza, A Schenffeldt, P Alarcón… - Veterinary immunology …, 2020 - Elsevier
Background Polymorphonuclear neutrophils (PMN) are the largest leukocyte population in
the blood of most mammals including horses, and play an important defensive role in many …

[HTML][HTML] Viral infection and allergy–What equine immune responses can tell us about disease severity and protection

EM Larson, B Wagner - Molecular Immunology, 2021 - Elsevier
Horses have many naturally occurring diseases that mimic similar conditions in humans.
The ability to conduct environmentally controlled experiments and induced disease studies …