Background Airway smooth muscle remodelling in severe equine asthma includes both
thickening of airway smooth muscle, resulting from hyperplasia and hypertrophy, and …

Neutrophilic inflammation is believed to contribute to the airway obstruction and remodelling
in equine asthma. Azithromycin, an antibiotic with immunomodulatory properties, reduces …

Neutrophils display an array of biological functions including the formation of neutrophil
extracellular traps (NETs), web-like structures specialized in trapping, neutralizing, killing …

Simple Summary The increase in the number of horses suffering from chronic respiratory
diseases prompted us to undertake research on markers useful in the quick and accurate …

The present work characterized the metabolomic profile of bronchoalveolar lavage fluid
(BALF) in healthy horses, experimentally-induced airway inflammation by …

Neutrophils play a major role in many equine conditions, including equine asthma, laminitis,
and intestinal ischemia and reperfusion injury, and therefore represent an attractive target …

Objective To explore the effect of 1, 25-dihydroxyvitamin D3 [1, 25-(OH) 2D3] on reactive
oxygen species (ROS) through transforming growth factor-β1 (TGF-β1)/(Smad2/3) and …

The objective of this study was to determine the extent that nebulized glycosylated caffeic
acid phenylether ester-4-O-alpha-D-glucopyranoside (G-CAPE) attenuates particulate …

Neutrophils participate in innate immunity as the first line of host defence against
microorganisms. However, persistent neutrophil activity and delayed apoptosis can be …

Neutrophils are terminally differentiated innate effector cells at the first line of host defense.
Neutrophil migration within tissues is complex and involves several steps, during which …