[HTML][HTML] Traumatic spinal cord injury: an overview of pathophysiology, models and acute injury mechanisms
A Alizadeh, SM Dyck, S Karimi-Abdolrezaee - Frontiers in neurology, 2019 - frontiersin.org
Traumatic spinal cord injury (SCI) is a life changing neurological condition with substantial
socioeconomic implications for patients and their care-givers. Recent advances in medical …
socioeconomic implications for patients and their care-givers. Recent advances in medical …
The biology of regeneration failure and success after spinal cord injury
Since no approved therapies to restore mobility and sensation following spinal cord injury
(SCI) currently exist, a better understanding of the cellular and molecular mechanisms …
(SCI) currently exist, a better understanding of the cellular and molecular mechanisms …
The translational landscape in spinal cord injury: focus on neuroplasticity and regeneration
TH Hutson, S Di Giovanni - Nature Reviews Neurology, 2019 - nature.com
Over the past decade, we have witnessed a flourishing of novel strategies to enhance
neuroplasticity and promote axon regeneration following spinal cord injury, and results from …
neuroplasticity and promote axon regeneration following spinal cord injury, and results from …
From basics to clinical: a comprehensive review on spinal cord injury
Spinal cord injury (SCI) is a devastating neurological disorder that affects thousands of
individuals each year. Over the past decades an enormous progress has been made in our …
individuals each year. Over the past decades an enormous progress has been made in our …
[HTML][HTML] Rho family GTPases: key players in neuronal development, neuronal survival, and neurodegeneration
TR Stankiewicz, DA Linseman - Frontiers in cellular neuroscience, 2014 - frontiersin.org
The Rho family of GTPases belongs to the Ras superfamily of low molecular weight (∼ 21
kDa) guanine nucleotide binding proteins. The most extensively studied members are RhoA …
kDa) guanine nucleotide binding proteins. The most extensively studied members are RhoA …
[HTML][HTML] Human dental pulp-derived stem cells promote locomotor recovery after complete transection of the rat spinal cord by multiple neuro-regenerative …
K Sakai, A Yamamoto, K Matsubara… - The Journal of …, 2012 - Am Soc Clin Investig
Spinal cord injury (SCI) often leads to persistent functional deficits due to loss of neurons
and glia and to limited axonal regeneration after injury. Here we report that transplantation of …
and glia and to limited axonal regeneration after injury. Here we report that transplantation of …
Restoring function after spinal cord injury: towards clinical translation of experimental strategies
Spinal cord injury is currently incurable and treatment is limited to minimising secondary
complications and maximising residual function by rehabilitation. Improved understanding of …
complications and maximising residual function by rehabilitation. Improved understanding of …
Glial inhibition of CNS axon regeneration
Damage to the adult CNS often leads to persistent deficits due to the inability of mature
axons to regenerate after injury. Mounting evidence suggests that the glial environment of …
axons to regenerate after injury. Mounting evidence suggests that the glial environment of …
Recent update on basic mechanisms of spinal cord injury
Spinal cord injury (SCI) is a life-shattering neurological condition that affects between
250,000 and 500,000 individuals each year with an estimated two to three million people …
250,000 and 500,000 individuals each year with an estimated two to three million people …
Therapeutic interventions after spinal cord injury
Spinal cord injury (SCI) can lead to paraplegia or quadriplegia. Although there are no fully
restorative treatments for SCI, various rehabilitative, cellular and molecular therapies have …
restorative treatments for SCI, various rehabilitative, cellular and molecular therapies have …