[HTML][HTML] The Single Toxin Origin of Alzheimer's Disease and Other Neurodegenerative Disorders Enables Targeted Approach to Treatment and Prevention
M Tolar, JA Hey, A Power, S Abushakra - International Journal of …, 2024 - mdpi.com
New data suggest that the aggregation of misfolded native proteins initiates and drives the
pathogenic cascade that leads to Alzheimer's disease (AD) and other age-related …
pathogenic cascade that leads to Alzheimer's disease (AD) and other age-related …
[HTML][HTML] Molecular mechanisms in pathophysiology of mucopolysaccharidosis and prospects for innovative therapy
Mucopolysaccharidoses (MPSs) are a group of inborn errors of the metabolism caused by a
deficiency in the lysosomal enzymes required to break down molecules called …
deficiency in the lysosomal enzymes required to break down molecules called …
[HTML][HTML] Is Alzheimer's disease an individual-centered disease? Hypotheses from the atomic levels up to mathematical models for biological systems
M Giorelli, D Accavone, A De Liso - Frontiers in Neurology, 2024 - frontiersin.org
© 2024 Giorelli, Accavone and De_liso. This is an open-access article distributed under the
terms of the Creative Commons Attribution License (CC BY). The use, distribution and …
terms of the Creative Commons Attribution License (CC BY). The use, distribution and …
Unveiling new thiazole‐clubbed piperazine derivatives as multitarget anti‐AD: Design, synthesis, and in silico studies
EE Nasr, SS Tawfik, MAM Massoud… - Archiv der …, 2024 - Wiley Online Library
New thiazole‐clubbed piperazine derivatives were designed, synthesized, evaluated for
their inhibitory capabilities against human acetylcholinesterase and butyrylcholinesterase …
their inhibitory capabilities against human acetylcholinesterase and butyrylcholinesterase …
[HTML][HTML] Targeting the molecular web of Alzheimer's disease: unveiling pathways for effective pharmacotherapy
D Jadhav, N Saraswat, N Vyawahare… - The Egyptian Journal of …, 2024 - Springer
Introduction Alzheimer's disease is a neurocognitive disorder that affects elderly people by
slowly impaired cognition, dementia, and gets worse with age. It slowly impacts the quality of …
slowly impaired cognition, dementia, and gets worse with age. It slowly impacts the quality of …
Anti-amyloid Monoclonal Antibodies in Alzheimer's Disease: A New Hope
A Nasibova, R Khalilov, A Eftekhari - International Journal of Aging, 2023 - ijage.com
Objectives: The current review aimed to collect the updated clinical investigations of
monoclonal antibodies (mAbs) in Alzheimer's disease (AD) patients and assess the …
monoclonal antibodies (mAbs) in Alzheimer's disease (AD) patients and assess the …