HIV pre‐exposure prophylaxis for adolescent girls and young women in Africa: from efficacy trials to delivery
CL Celum, S Delany‐Moretlwe… - Journal of the …, 2019 - Wiley Online Library
Introduction Adolescent girls and young women (AGYW) in Africa have high HIV incidence
despite scale‐up of HIV testing and HIV treatment. Placebo‐controlled trials of tenofovir …
despite scale‐up of HIV testing and HIV treatment. Placebo‐controlled trials of tenofovir …
[HTML][HTML] Canadian guideline on HIV pre-exposure prophylaxis and nonoccupational postexposure prophylaxis
Methods The guideline was developed by the Biomedical HIV Prevention Working Group of
the CIHR Canadian HIV Trials Network, with funding from the Canadian Institutes of Health …
the CIHR Canadian HIV Trials Network, with funding from the Canadian Institutes of Health …
[HTML][HTML] Integrating preexposure prophylaxis delivery in routine family planning clinics: a feasibility programmatic evaluation in Kenya
KK Mugwanya, J Pintye, J Kinuthia, F Abuna… - PLoS …, 2019 - journals.plos.org
Background Young women account for a disproportionate fraction of new HIV infections in
Africa and are a priority population for HIV prevention, including implementation of …
Africa and are a priority population for HIV prevention, including implementation of …
[HTML][HTML] Uptake, engagement, and adherence to pre-exposure prophylaxis offered after population HIV testing in rural Kenya and Uganda: 72-week interim analysis of …
CA Koss, ED Charlebois, J Ayieko, D Kwarisiima… - The lancet HIV, 2020 - thelancet.com
Background Optimal strategies for pre-exposure prophylaxis (PrEP) engagement in
generalised HIV epidemics are unknown. We aimed to assess PrEP uptake and …
generalised HIV epidemics are unknown. We aimed to assess PrEP uptake and …
[HTML][HTML] Safety, adherence, and HIV-1 seroconversion among women using the dapivirine vaginal ring (DREAM): an open-label, extension study
A Nel, N Van Niekerk, B Van Baelen, M Malherbe… - The Lancet …, 2021 - thelancet.com
Summary Background The Ring Study, a phase 3 trial in 1959 sexually active women
(randomised 2: 1), showed a favourable safety profile and a 31% HIV-1 infection risk …
(randomised 2: 1), showed a favourable safety profile and a 31% HIV-1 infection risk …
Safety, uptake, and use of a dapivirine vaginal ring for HIV-1 prevention in African women (HOPE): an open-label, extension study
JM Baeten, T Palanee-Phillips, NM Mgodi, AJ Mayo… - The lancet HIV, 2021 - thelancet.com
Background Two phase 3 clinical trials showed that use of a monthly vaginal ring containing
25 mg dapivirine was well tolerated and reduced HIV-1 incidence in women by …
25 mg dapivirine was well tolerated and reduced HIV-1 incidence in women by …
[HTML][HTML] HIV pre-exposure prophylaxis and early antiretroviral treatment among female sex workers in South Africa: results from a prospective observational …
R Eakle, GB Gomez, N Naicker, R Bothma… - PLoS …, 2017 - journals.plos.org
Background Operational research is required to design delivery of pre-exposure prophylaxis
(PrEP) and early antiretroviral treatment (ART). This paper presents the primary analysis of …
(PrEP) and early antiretroviral treatment (ART). This paper presents the primary analysis of …
PrEP rollout in Africa: status and opportunity
EM Irungu, JM Baeten - Nature medicine, 2020 - nature.com
Following recommendations by the World Health Organization in 2015, and key clinical
trials, countries in sub-Saharan Africa, the region with the highest burden of human …
trials, countries in sub-Saharan Africa, the region with the highest burden of human …
Understanding demand for PrEP and early experiences of PrEP use among young adults in rural Kenya and Uganda: a qualitative study
CS Camlin, CA Koss, M Getahun, L Owino, H Itiakorit… - AIDS and Behavior, 2020 - Springer
Few studies have sought to understand factors influencing uptake and continuation of pre-
exposure prophylaxis (PrEP) among young adults in sub-Saharan Africa in the context of …
exposure prophylaxis (PrEP) among young adults in sub-Saharan Africa in the context of …