In autoimmune neurologic disorders, the blood–brain barrier (BBB) plays a central role in
immunopathogenesis, since this vascular interface is an entry path for cells and effector …

The human genome encodes a vast repertoire of protein non-coding RNAs (ncRNA), some
specific to the brain. MicroRNAs, which interfere with the translation of target mRNAs, are of …

Psychoactive drugs frequently contaminate aquatic environments after human consumption,
raising concerns about their residues and ecological harm. This study investigates the …

Systemic lupus erythematosus is an autoimmune disease affecting multiple organs with
devastating pathological consequences. Current treatment regimens largely rely on …

Sepsis is not only a significant cause of mortality worldwide but has particularly devastating
effects on the central nervous system of survivors. It is therefore crucial to understand the …

The complement system, an arm of the innate immune system plays a critical role in both
health and disease. The complement system is highly complex with dual possibilities …

Neuropsychiatric disease is one of the most common manifestations of human systemic
lupus erythematosus, but the mechanisms remain poorly understood. In human brain …

The deposition of immune complexes (ICs) in tissues induces a “type III hypersensitivity” that
results in tissue damage and underlies the pathogenesis of many autoimmune diseases …

Choroid plexus (CP) enlargement is proposed as a marker of neuroinflammation in immune-
mediated conditions. CP involvement has also been hypothesized in the immunopathology …

Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease that can
involve nervous system commitment known as neuropsychiatric systemic lupus …