[HTML][HTML] Focus: antimicrobial resistance: antimicrobial peptides therapy: an emerging alternative for treating drug-resistant bacteria

IE Mba, EI Nweze - The Yale journal of biology and medicine, 2022 - ncbi.nlm.nih.gov
Microbial resistance to antibiotics is an ancient and dynamic issue that has brought a
situation reminiscent of the pre-antibiotic era to the limelight. Currently, antibiotic resistance …

In pursuit of next-generation therapeutics: Antimicrobial peptides against superbugs, their sources, mechanism of action, nanotechnology-based delivery, and clinical …

A Thakur, A Sharma, HK Alajangi, PK Jaiswal… - International Journal of …, 2022 - Elsevier
Antimicrobial peptides (AMPs) attracted attention as potential source of novel antimicrobials.
Multi-drug resistant (MDR) infections have emerged as a global threat to public health in …

Antimicrobial peptide octominin-encapsulated chitosan nanoparticles enhanced antifungal and antibacterial activities

EHTT Jayathilaka, C Nikapitiya, M De Zoysa… - International Journal of …, 2022 - mdpi.com
Antimicrobial peptides (AMPs) have become a key solution for controlling multi-drug-
resistant (MDR) pathogens, and the nanoencapsulation of AMPs has been used as a …

Antimicrobial Peptides Demonstrate Activity against Resistant Bacterial Pathogens

M Garvey - Infectious Disease Reports, 2023 - mdpi.com
The antimicrobial resistance crisis is an ongoing major threat to public health safety. Low-
and middle-income countries are particularly susceptible to higher fatality rates and the …

Traditional and computational screening of non-toxic peptides and approaches to improving selectivity

AA Robles-Loaiza, EA Pinos-Tamayo, B Mendes… - Pharmaceuticals, 2022 - mdpi.com
Peptides have positively impacted the pharmaceutical industry as drugs, biomarkers, or
diagnostic tools of high therapeutic value. However, only a handful have progressed to the …

[HTML][HTML] Design methods for antimicrobial peptides with improved performance

J Mwangi, PM Kamau, RC Thuku, R Lai - Zoological Research, 2023 - ncbi.nlm.nih.gov
The recalcitrance of pathogens to traditional antibiotics has made treating and eradicating
bacterial infections more difficult. In this regard, developing new antimicrobial agents to …

Orientational Nanoconjugation with Gold Endows Marked Antimicrobial Potential and Drugability of Ultrashort Dipeptides

Z Zhang, Y Chen, J Gao, M Yang, D Zhang, L Wang… - Nano Letters, 2023 - ACS Publications
Antibiotic resistance is a global threat. Antimicrobial peptides (AMPs) are highly desirable to
treat multidrug-resistant pathogen infection. However, few AMPs are clinically available, due …

Challenges and advances in antimicrobial peptide development

KBS de Oliveira, ML Leite, VA Cunha, NB da Cunha… - Drug Discovery …, 2023 - Elsevier
Microbial resistance is a major concern for public health worldwide, mainly because of the
inappropriate use of antimicrobials. In this scenario, antimicrobial peptides (AMPs) have …

S100 proteins as novel therapeutic targets in psoriasis and other autoimmune diseases

K Kurpet, G Chwatko - Molecules, 2022 - mdpi.com
Psoriasis is one of the most common inflammatory skin diseases affecting about 1–3% of the
population. One of the characteristic abnormalities in psoriasis is the excessive production of …

The current research status and strategies employed to modify food-derived bioactive peptides

JJ Majura, W Cao, Z Chen, KK Htwe, W Li, R Du… - Frontiers in …, 2022 - frontiersin.org
The ability of bioactive peptides to exert biological functions has mainly contributed to their
exploitation. The exploitation and utilization of these peptides have grown tremendously …