General anesthetics and vascular smooth muscle: direct actions of general anesthetics on cellular mechanisms regulating vascular tone
T Akata, DC Warltier - The Journal of the American Society of …, 2007 - pubs.asahq.org
General anesthetics threaten cardiovascular stability by causing changes in cardiac
function, vascular reactivity, and cardiovascular reflexes and significantly alter distribution of …
function, vascular reactivity, and cardiovascular reflexes and significantly alter distribution of …
Variants of the promoter of MYH6 gene in congenital isolated and sporadic patent ductus arteriosus: case-control study and cellular functional analyses
JY Zuo, HX Chen, Q Yang, GW He - Human Molecular Genetics, 2024 - academic.oup.com
Patent ductus arteriosus (PDA) is a common form of congenital heart disease. The MYH6
gene has important effects on cardiovascular growth and development, but the effect of …
gene has important effects on cardiovascular growth and development, but the effect of …
Protein kinases participate in the contraction in response to levobupivacaine in the rat aorta
HS Shim, SH Ok, SH Lee, SC Kwon, JT Sohn - European journal of …, 2012 - Elsevier
Levobupivacaine is a long-acting amide local anesthetic that intrinsically produces
vasoconstriction both in vivo and in vitro. Levobupivacaine increases intracellular calcium …
vasoconstriction both in vivo and in vitro. Levobupivacaine increases intracellular calcium …
[HTML][HTML] Differential effects on the mesenteric microcirculatory response to vasopressin and phenylephrine after cardiopulmonary bypass
OBJECTIVE: Mesenteric ischemia is a rare but potentially devastating complication of
cardiac surgery with cardiopulmonary bypass. We hypothesized that alterations in mitogen …
cardiac surgery with cardiopulmonary bypass. We hypothesized that alterations in mitogen …
The mechanism behind the inhibitory effect of isoflurane on angiotensin II-induced vascular contraction is different from that of sevoflurane
A Ishikawa, K Ogawa, Y Tokinaga… - Anesthesia & …, 2007 - journals.lww.com
BACKGROUND: Angiotensin II (Ang II)-induced vascular contraction is mediated both by a
Ca 2+-mediated signaling pathway and a Ca 2+ sensitization mechanism. We recently …
Ca 2+-mediated signaling pathway and a Ca 2+ sensitization mechanism. We recently …
The effect of anesthetic preconditioning with sevoflurane on intracellular signal-transduction pathways and apoptosis, in a lung autotransplant experimental model
I Garutti, F Gonzalez-Moraga… - Revista Brasileira de …, 2019 - SciELO Brasil
Background: Anesthetic pre-conditioning attenuates inflammatory response during ischemia-
reperfusion lung injury. The molecular mechanisms to explain it are not fully understood …
reperfusion lung injury. The molecular mechanisms to explain it are not fully understood …
Phosphatidylinositol 3-kinase inhibition induces vasodilator effect of sevoflurane via reduction of Rho kinase activity
Y Miyamoto, GG Feng, S Satomi, K Tanaka, Y Fujiwara… - Life Sciences, 2017 - Elsevier
Aims This study was aimed to examine whether a volatile anesthetic sevoflurane in clinical
doses reduces vasoconstriction under the inhibition of phosphatidylinositol 3-kinase (PI3K) …
doses reduces vasoconstriction under the inhibition of phosphatidylinositol 3-kinase (PI3K) …
Sevoflurane inhibits angiotensin II-induced Rho kinase-mediated contraction of vascular smooth muscle from spontaneously hypertensive rat
N Uematsu, K Ogawa, Y Tokinaga, K Tange… - Journal of …, 2011 - Springer
Abstract Purpose Angiotensin II (Ang II)-induced vasoconstriction is mediated by changes in
intracellular free Ca 2+ concentration ([Ca 2+] i) and myofilament Ca 2+ sensitivity. Protein …
intracellular free Ca 2+ concentration ([Ca 2+] i) and myofilament Ca 2+ sensitivity. Protein …
麻醉药对血管收缩反应性的影响
于金贵 - 国际麻醉学与复苏杂志, 2007 - cqvip.com
全身麻醉药在临床上常引起剂量依赖性血压下降, 直接扩血管作用是其诱发低血压的重要原因之
一. 血管平滑肌(VSM) 收缩反应由细胞内钙离子浓度([Ca^ 2+] i) 升高激发 …
一. 血管平滑肌(VSM) 收缩反应由细胞内钙离子浓度([Ca^ 2+] i) 升高激发 …
Sevoflurane does not alter norepinephrine-induced intracellular Ca^ sup 2+^ changes in the diabetic rat aorta
K Fujii, K Ogawa, Y Tokinaga… - Canadian Journal of …, 2010 - search.proquest.com
The effect of volatile anesthetics on the mechanism (s) of vascular contraction in diabetes
mellitus (DM) has not been fully understood. The current study was designed to determine …
mellitus (DM) has not been fully understood. The current study was designed to determine …