Cognitive and behavioural flexibility: neural mechanisms and clinical considerations

LQ Uddin - Nature Reviews Neuroscience, 2021 - nature.com
Cognitive and behavioural flexibility permit the appropriate adjustment of thoughts and
behaviours in response to changing environmental demands. Brain mechanisms enabling …

[HTML][HTML] Anterior insula as a gatekeeper of executive control

I Molnar-Szakacs, LQ Uddin - Neuroscience & Biobehavioral Reviews, 2022 - Elsevier
Executive control is a complex high-level cognitive function that relies on distributed brain
circuitry. We propose that the anterior insular cortex plays an under-appreciated role in …

Principles of cognitive control over task focus and task switching

T Egner - Nature Reviews Psychology, 2023 - nature.com
Adaptive behaviour requires the ability to focus on a task and protect it from distraction
(cognitive stability) and to rapidly switch tasks when circumstances change (cognitive …

[HTML][HTML] What have we really learned from functional connectivity in clinical populations?

J Zhang, A Kucyi, J Raya, AN Nielsen, JS Nomi… - NeuroImage, 2021 - Elsevier
Functional connectivity (FC), or the statistical interdependence of blood-oxygen dependent
level (BOLD) signals between brain regions using fMRI, has emerged as a widely used tool …

Brain dynamics underlying cognitive flexibility across the lifespan

L Kupis, ZT Goodman, S Kornfeld, S Hoang… - Cerebral …, 2021 - academic.oup.com
The neural mechanisms contributing to flexible cognition and behavior and how they
change with development and aging are incompletely understood. The current study …

Developmental neuroimaging of cognitive flexibility: update and future directions

LB Kupis, LQ Uddin - Annual Review of Developmental …, 2023 - annualreviews.org
Cognitive flexibility, or the ability to mentally switch between tasks according to changing
environmental demands, supports optimal life outcomes, making it an important executive …

“No way out except from external intervention”: First-hand accounts of autistic inertia

KL Buckle, K Leadbitter, E Poliakoff… - Frontiers in …, 2021 - frontiersin.org
This study, called for by autistic people and led by an autistic researcher, is the first to
explore 'autistic inertia,'a widespread and often debilitating difficulty acting on their …

Alterations in connectome dynamics in autism spectrum disorder: a harmonized mega-and meta-analysis study using the autism brain imaging data exchange dataset

Y Xie, Z Xu, M Xia, J Liu, X Shou, Z Cui, X Liao, Y He - Biological Psychiatry, 2022 - Elsevier
Background Neuroimaging studies have reported functional connectome aberrancies in
autism spectrum disorder (ASD). However, the time-varying patterns of connectome …

Mapping the heterogeneous brain structural phenotype of autism spectrum disorder using the normative model

X Shan, LQ Uddin, J Xiao, C He, Z Ling, L Li… - Biological …, 2022 - Elsevier
Background Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder
characterized by substantial clinical and biological heterogeneity. Quantitative and …

Everyday executive function issues from the perspectives of Autistic adolescents and their parents: Theoretical and empirical implications

L Kenny, A Remington, E Pellicano - Autism, 2024 - journals.sagepub.com
There is a long tradition of research into autistic people's executive function skills. Yet,
despite decades of research on EF in autism, the existing literature remains contradictory …