Electrospun polymer/apatite composite scaffolds are promising candidates as functional
bone substitutes because of their ability to allow pre-osteoblast attachment, proliferation …

Pluripotent cells represent a powerful tool for tissue regeneration, but their clinical utility is
limited by their propensity to form teratomas. Little is known about their interaction with the …

Despite the high innate regenerative capacity of bone, large osseous defects fail to heal and
remain a clinical challenge. Healing such defects requires the formation of large amounts of …

The nanostructured surface of biomaterials plays an important role in improving their in vitro
cellular bioactivity as well as stimulating in vivo tissue regeneration. Inspired by the mussel's …

Surface modification enables the creation of bioactive implants using traditional material
substrates without altering the mechanical properties of the bulk material. For applications …

Abstract A novel PCL/HA/TiO 2 hybrid coating on ZM21 Mg alloy substrate has been
investigated for corrosion resistance, biocompatibility and mechanical integrity loss in terms …

Bone morphogenetic proteins (BMPs) are currently approved for spinal fusion, tibial fracture
repair, and maxillofacial bone regeneration. However, BMP pleiotropism, paradoxical …

Three-dimensional (3D) printing provides a novel approach to repair bone defects using
customized biomimetic tissue scaffolds. To make a bone substitute closest to natural bone …

Developing patient-specific biomedical implants for clinical application requires the
integration of material science, manufacturing engineering, and biology. As selective laser …

An understanding of the cytoskeleton's importance in stem cells is essential for their
manipulation and further clinical application. The cytoskeleton is crucial in stem cell biology …