Polymer–ceramic composites are favourite candidates when aiming to replace bone tissue.
We present here scaffolds made of polycaprolactone-hydroxyapatite (PCL-HAp) composites …

Synthetic biomaterials are used to overcome the limited quantity of human-derived
biomaterials and to impart additional biofunctionality. Although numerous synthetic …

Objective The aim of this study was the synthesis and analysis of the tissue reaction to three
different Hydroxyapatite (HA)‐based bone substitute materials differing only in granule size …

Native bone tissue is composed of a complex matrix of collagen, non-collagenous proteins,
and hydroxyapatite (HAP). Bone sialoprotein (BSP) and bone osteopontin (OPN) are …

The behavior of cells responsible for bone formation, osseointegration, and bone bonding in
vivo are governed by both the surface chemistry and topography of scaffold matrices. Bone …

We report here a new versatile method to deposit discrete hydroxyapatite (HA) nanoparticles
on a titanium (Ti) implant with predisposing substrate microtopography, which exhibited an …

Although adipose-derived stem cells (ASCs) are an attractive cell source for bone tissue
engineering, direct use of ASCs alone has had limited success in the treatment of large …

Reconstructing segmental mandiblular defects remains a challenge in the clinic. Tissue
engineering strategies provide an alternative option to resolve this problem. The objective of …

Background Many clinical studies have shown a correlation between proton pump inhibitors
(PPIs) and osteoporosis or fractures. The purpose of this study was to establish a murine …

In this study, biodegradable poly (lactide-co-glycolide)(PLGA)(70/30) films and scaffolds
were first treated with oxygen plasma and then incubated in a modified simulated body fluid …