Background Aplastic anaemia is a bone-marrow-failure syndrome characterised by low
blood-cell counts and fatty bone marrow. In most cases, no obvious aetiological factor can …

Recent epidemiological and immunological studies provide evidence for an association
between Epstein–Barr virus infection and multiple sclerosis, suggesting a role of Epstein …

It has long been known that multiple sclerosis (MS) is associated with an increased Epstein-
Barr virus (EBV) seroprevalence and high immune reactivity to EBV and that infectious …

Clonal expansion of B cells and the production of oligoclonal IgG in the brain and
cerebrospinal fluid (CSF) of patients with multiple sclerosis (MS) have long been interpreted …

Background: Because common viruses are encountered during childhood, pediatric multiple
sclerosis (MS) offers a unique opportunity to investigate the influence of these viruses on …

Environmental factors account for 75% of the risk of developing multiple sclerosis (MS).
Numerous infections have been suspected as environmental disease triggers, but none of …

An association between multiple sclerosis (MS) and the human leukocyte antigen (HLA)
complex, a dense cluster of genes on the short arm of chromosome 6, was first noted over …

Multiple sclerosis (MS) is a common chronic inflammatory demyelinating disease of the
central nervous system (CNS) causing progressive disability. Many observations implicate …

Cytokines play an important role in the pathogenesis of inflammatory diseases including
multiple sclerosis (MS). Experimental models have played a critical role in unraveling the …

This review summarizes and integrates research on vitamin D and CD4+ T-lymphocyte
biology to develop new mechanistic insights into the molecular etiology of autoimmune …