Rapid antimicrobial action is an important advantage of antimicrobial peptides (AMPs) over
antibiotics, which is also a reason for AMPs being less likely to induce bacterial resistance …

The development of biopolymers for biomedical applications has traditionally been based
on new chemistries. However, there is growing recognition that the biological responses can …

Particulate matter (PM) exposure disrupts the skin barrier, causing cutaneous inflammation
that may eventually contribute to the development of various skin diseases. Herein, we …

The cell membrane permeabilization ability of immune defense antimicrobial peptides
(AMPs) is widely applied in biomedicine. Although the mechanisms of peptide–membrane …

A real-time and molecule-level monitoring of the interfacial dynamic interactions between
molecules and a cell membrane is of vital importance. Herein, taking TAT, one of the most …

Peptide design and drug development offer a promising solution for combating serious
diseases or infections. In this study, using an AI–human negotiation approach, we have …

LL-37, the only human host cathelicidin peptide, is proposed to be able to induce host cell
apoptosis through mitochondrial membrane permeabilization (MMP). Detailed pathways of …

Polymyxin B (PMB) is clinically used as a last-line therapy against life-threatening Gram-
negative “superbugs”. However, thorough understanding of the membrane actions of PMB at …

Recent studies have demonstrated the crucial role of cholesterol (Chol) in regulating the
mechanical properties and biological functions of cell membranes. Methyl-β-cyclodextrin …

Small-sized fluorescent carbon dots (CDs) are gaining increasing attention in the field of
biomedical applications. The environmental and biological compatibility of positively …