Anticoagulation in chronic hemodialysis: progress toward an optimal approach

M Kessler, F Moureau, P Nguyen - Seminars in Dialysis, 2015 - Wiley Online Library
Appropriate anticoagulation for hemodialysis (HD) requires a subtle balance between under‐
and over‐heparinization to prevent extracorporeal circuit (ECC) clotting and bleeding …

The contact activation inhibitor AB023 in heparin-free hemodialysis: results of a randomized phase 2 clinical trial

CU Lorentz, EI Tucker, NG Verbout… - Blood, The Journal …, 2021 - ashpublications.org
End-stage renal disease (ESRD) patients on chronic hemodialysis have repeated blood
exposure to artificial surfaces that can trigger clot formation within the hemodialysis circuit …

An official ATS/ERS/ESICM/SCCM/SRLF statement: prevention and management of acute renal failure in the ICU patient: an international consensus conference in …

L Brochard, F Abroug, M Brenner… - American Journal of …, 2010 - atsjournals.org
Objectives: To address the issues of Prevention and Management of Acute Renal Failure in
the ICU Patient, using the format of an International Consensus Conference. Methods and …

Anticoagulation management in haemodialysis patients with atrial fibrillation: evidence and opinion

AS De Vriese, G Heine - Nephrology Dialysis Transplantation, 2022 - academic.oup.com
In the absence of robust evidence to guide clinical decision-making, the optimal approach to
prevent stroke and systemic embolism in haemodialysis (HD) patients with atrial fibrillation …

Recent advancement challenges with synthesis of biocompatible hemodialysis membranes

SU Zaman, S Rafiq, A Ali, MS Mehdi, A Arshad… - Chemosphere, 2022 - Elsevier
The focus of this study is to enhance the protein fouling resistance, hydrophilicity,
biocompatibility, hemocompatibility and ability of the membranes and to reduce health …

[HTML][HTML] Results of the HepZero study comparing heparin-grafted membrane and standard care show that heparin-grafted dialyzer is safe and easy to use for heparin …

M Laville, M Dorval, JF Ros, R Fay, J Cridlig… - Kidney international, 2014 - Elsevier
Heparin is used to prevent clotting during hemodialysis, but heparin-free hemodialysis is
sometimes needed to decrease the risk of bleeding. The HepZero study is a randomized …

Stroke prophylaxis in patients with atrial fibrillation and end-stage renal disease

M van Zyl, HM Abdullah, PA Noseworthy… - Journal of Clinical …, 2020 - mdpi.com
Atrial fibrillation (AF) is an important comorbidity in patients with end-stage renal disease
(ESRD) undergoing dialysis that portends increased health care utilization, morbidity, and …

Advances in polysulfone-based membranes for hemodialysis

IG Wenten, PTP Aryanti, K Khoiruddin… - Journal of Membrane …, 2016 - msrjournal.com
The polysulfone-based membrane has been used in hemodialysis (HD) and it is
continuously developed to maintain its sustainability on the subject of biocompatibility …

Should dialysis patients ever receive warfarin and for what reasons?

WM Bennett - Clinical Journal of the American Society of …, 2006 - journals.lww.com
It has been common practice for dialysis patients with problematic vascular access to
receive warfarin for the purposes of keeping the access functional. This, of course, increases …

Rationale and design of the HepZero study: a prospective, multicenter, international, open, randomized, controlled clinical study with parallel groups comparing …

P Rossignol, M Dorval, R Fay, JF Ros, N Loughraieb… - Trials, 2013 - Springer
Background Anticoagulation for chronic dialysis patients with contraindications to heparin
administration is challenging. Current guidelines state that in patients with increased …