In mammals, the development of male or female gonads from fetal bipotential gonads
depends on intricate genetic networks. Changes in dosage or temporal expression of sex …

Male infertility is a multifactorial and heterogeneous pathological condition affecting 7% of
the general male population. The genetic landscape of male infertility is highly complex as …

Overview of genetics of disorders of sexual development : Current Opinion in Pediatrics
Overview of genetics of disorders of sexual development : Current Opinion in Pediatrics Log …

Pigs serve as a robust animal model for the study of human diseases, notably in the context
of disorders of sex development (DSD). This study aims to investigate the phenotypic …

We report a case of a fetus with 46, XX testicular disorder of sex development detected
prenatally. This fetus was found abnormally due to non‐invasive prenatal testing …

Summary 46, XX male sex reversal syndrome is one of the rarest sex chromosomal
aberrations. The presence of SRY gene on one of the X chromosomes is the most frequent …

Prenatal diagnosis of a sex chromosome abnormality (SCA) may sometimes be suspected
with particular ultrasound abnormalities, but more often it is unexpected. Although many …

A genetic etiology of male infertility is identified in fewer than 25% of infertile men, while 30%
of infertile men lack a clear etiology, resulting in a diagnosis of idiopathic male infertility …

Materials and Methods High-molecular weight DNA was extracted from 15 mL of amniotic
fluid, using the Promega Wizard Genomic DNA Purification Kit (Madison, WI, USA). A …

The translocation of the testis-determining factor, the SRY gene, from the Y to the X
chromosome is a rare event that causes abnormalities in gonadal development. In all cases …