Acute renal failure (ARF), classically defined as an abrupt decrease in kidney function that
leads to accumulation of nitrogenous wastes such as blood urea nitrogen and creatinine, is …

There are a number of conditions of the bladder that can lead to loss of function. Many of
these require reconstructive procedures. However, current techniques may lead to a number …

Applications of regenerative medicine technology may offer novel therapies for patients with
injuries, end-stage organ failure, or other clinical problems. Currently, patients suffering from …

In recent years, increasing evidence has been provided that even minor renal dysfunction is
a powerful cardiovascular risk factor that induces typical cardiovascular alterations and thus …

Neonephrogenesis, the capacity to regenerate renal tissue, is a distinctive feature of fish but
not usually of mammals. However, evidence exists for kidney repair in response to insulting …

All animals must excrete the waste products of metabolism. Excretion is performed by the
kidney in vertebrates and by the Malpighian tubules in Drosophila. The mammalian kidney …

Most hypertensive cases are primary and heavily associated with modifiable risk factors like
salt intake. Evidence suggests that even small reductions in salt consumption reduce blood …

Abstract The Rex-1 (Zfp-42) gene encodes a zinc finger family transcription factor which is
highly expressed in mouse and human embryonic stem cells. It is one of several gene …

BACKGROUND: Accelerated atherosclerosis in patients with chronic kidney disease (CKD)
is still incompletely understood. Angiopoietin 1 (Ang-1) and Ang-2 are 55-kDa antagonistic …

Kidney disease is an escalating burden all over the world. In addition to preventing kidney
injury, regenerating damaged renal tissue is as important as to retard the progression of …