BackgroundPrevious research has established the relationship between cannabis use and
psychotic disorders. Whether cannabis use is related to transition to psychosis in patients at …

Background Studies report contrasting results regarding the efficacy and safety of
pharmacological, psychological, and combined interventions in psychosis and …

Prodromal features of the schizophrenia syndrome have been described for a century, and
work in the past two decades has produced a substantial literature based on these features …

Background. Several psychometric instruments are available for the diagnostic interview of
subjects at ultra high risk (UHR) of psychosis. Their diagnostic comparability is unknown …

Despite the wealth of evidence linking duration of untreated psychosis to critical illness
outcomes, most clinicians do not utilize any formal evaluation tools to identify attenuated or …

Background: Attenuated positive psychotic symptoms represent the defining features of the
clinical high-risk for psychosis (CHR-P) criteria. The effectiveness of each available …

Background Psychosis can be associated with acute recreational drug and novel
psychoactive substance (NPS) toxicity. However, there is limited data available on how …

Abstract Background and Hypothesis Individuals at clinical high risk for psychosis (CHR-p)
are less fit than nonclinical peers and show hippocampal abnormalities that relate to clinical …

Inflammation is involved in the pathophysiology of many chronic diseases, such as
rheumatoid arthritis and neurodegenerative diseases. Several studies have evidenced …

Background Transition to psychotic disorder has been the traditional outcome of interest for
research in the at-risk mental state (ARMS). However, there is growing recognition that …