Association of baseline inflammatory markers and the development of negative symptoms in individuals at clinical high risk for psychosis
Negative symptoms are common in individuals at clinical high-risk (CHR) for psychosis and
are associated with worse functional outcomes. Inflammation may be one mechanism …
are associated with worse functional outcomes. Inflammation may be one mechanism …
The Maudsley environmental risk score for psychosis
BackgroundRisk prediction algorithms have long been used in health research and practice
(eg prediction of cardiovascular disease and diabetes). However, similar tools have not …
(eg prediction of cardiovascular disease and diabetes). However, similar tools have not …
Cognitive behavioral therapy for prodromal stage of psychosis—outcomes for transition, functioning, distress, and quality of life: a systematic review and meta-analysis
Y Zheng, T Xu, Y Zhu, C Li, J Wang… - Schizophrenia …, 2022 - academic.oup.com
Objective This study aimed to provide insight into the efficacy of cognitive-behavioral therapy
for psychosis (CBTp) in patients with “clinical high risk of psychosis (CHR-P)”. Methods …
for psychosis (CBTp) in patients with “clinical high risk of psychosis (CHR-P)”. Methods …
Specificity of incident diagnostic outcomes in patients at clinical high risk for psychosis
JR Webb, J Addington, DO Perkins… - Schizophrenia …, 2015 - academic.oup.com
It is not well established whether the incident outcomes of the clinical high-risk (CHR)
syndrome for psychosis are diagnostically specific for psychosis or whether CHR patients …
syndrome for psychosis are diagnostically specific for psychosis or whether CHR patients …
The NEURAPRO biomarker analysis: long-chain omega-3 fatty acids improve 6-month and 12-month outcomes in youths at ultra-high risk for psychosis
GP Amminger, B Nelson, C Markulev, HP Yuen… - Biological …, 2020 - Elsevier
Background NEURAPRO was a multicenter, placebo-controlled trial of long-chain omega-3
polyunsaturated fatty acids (n-3 PUFAs)(fish oil) in 304 individuals at ultra-high risk for …
polyunsaturated fatty acids (n-3 PUFAs)(fish oil) in 304 individuals at ultra-high risk for …
NICE CG178 Psychosis and Schizophrenia in Adults: Treatment and Management–an evidence-based guideline?
M Taylor, U Perera - The British Journal of Psychiatry, 2015 - cambridge.org
National Institute for Health and Care Excellence (NICE) clinical guideline (CG) 178 was
published in 2014. NICE guidelines occupy an important international position. We argue …
published in 2014. NICE guidelines occupy an important international position. We argue …
Increased occipital gyrification and development of psychotic disorders in individuals with an at-risk mental state: a multicenter study
D Sasabayashi, Y Takayanagi, T Takahashi, S Koike… - Biological …, 2017 - Elsevier
Background Anomalies of brain gyrification have been reported in schizophrenia, possibly
reflecting its neurodevelopmental pathology. However, it remains elusive whether …
reflecting its neurodevelopmental pathology. However, it remains elusive whether …
Baseline demographics, clinical features and predictors of conversion among 200 individuals in a longitudinal prospective psychosis-risk cohort
G Brucato, MD Masucci, LY Arndt… - Psychological …, 2017 - cambridge.org
BackgroundDSM-5 proposes an Attenuated Psychosis Syndrome (APS) for further
investigation, based upon the Attenuated Positive Symptom Syndrome (APSS) in the …
investigation, based upon the Attenuated Positive Symptom Syndrome (APSS) in the …
Prepubertal environmental enrichment prevents dopamine dysregulation and hippocampal hyperactivity in MAM schizophrenia model rats
Background Schizophrenia (SCZ) is a neurodevelopmental disorder with a progressive,
prolonged course. Early prevention for SCZ is promising but overall lacks support from …
prolonged course. Early prevention for SCZ is promising but overall lacks support from …
Canadian guidelines for the pharmacological treatment of schizophrenia spectrum and other psychotic disorders in children and youth
S Abidi, I Mian, I Garcia-Ortega… - The Canadian …, 2017 - journals.sagepub.com
Objective: Schizophrenia spectrum and other psychotic disorders often have their onset in
adolescence. The sequelae of these illnesses can negatively alter the trajectory of …
adolescence. The sequelae of these illnesses can negatively alter the trajectory of …