[HTML][HTML] The role of Bcl-2 family member BNIP3 in cell death and disease: NIPping at the heels of cell death
TR Burton, SB Gibson - Cell Death & Differentiation, 2009 - nature.com
Bcl-2 nineteen-kilodalton interacting protein (BNIP3) is a BH-3-only Bcl-2 family member
whose expression levels increase during stress such as hypoxia through hypoxia-inducing …
whose expression levels increase during stress such as hypoxia through hypoxia-inducing …
Molecular mechanisms of castration-resistant prostate cancer progression
SS Dutt, AC Gao - Future oncology, 2009 - Taylor & Francis
Hormone-refractory prostate cancer is the result of regrowth of prostate cancer cells that
have adapted to the hormone-deprived environment of the prostate. The process by which …
have adapted to the hormone-deprived environment of the prostate. The process by which …
[HTML][HTML] Discovery and validation of a prostate cancer genomic classifier that predicts early metastasis following radical prostatectomy
Purpose Clinicopathologic features and biochemical recurrence are sensitive, but not
specific, predictors of metastatic disease and lethal prostate cancer. We hypothesize that a …
specific, predictors of metastatic disease and lethal prostate cancer. We hypothesize that a …
Interleukin-8 is a molecular determinant of androgen independence and progression in prostate cancer
S Araki, Y Omori, D Lyn, RK Singh, DM Meinbach… - Cancer research, 2007 - AACR
The proinflammatory chemokine interleukin-8 (IL-8) is undetectable in androgen-responsive
prostate cancer cells (eg, LNCaP and LAPC-4), but it is highly expressed in androgen …
prostate cancer cells (eg, LNCaP and LAPC-4), but it is highly expressed in androgen …
[HTML][HTML] Identification of the epigenetic reader CBX2 as a potential drug target in advanced prostate cancer
PL Clermont, F Crea, YT Chiang, D Lin, A Zhang… - Clinical …, 2016 - Springer
Background While localized prostate cancer (PCa) can be effectively cured, metastatic
disease inevitably progresses to a lethal state called castration-resistant prostate cancer …
disease inevitably progresses to a lethal state called castration-resistant prostate cancer …
[HTML][HTML] Role of transmembrane 4 L six family 1 in the development and progression of cancer
F Fu, X Yang, M Zheng, Q Zhao, K Zhang… - Frontiers in molecular …, 2020 - frontiersin.org
Transmembrane 4 L six family 1 (TM4SF1) is a protein with four transmembrane domains
that belongs to the transmembrane 4 L six family members (TM4SFs). Structurally, TM4SF1 …
that belongs to the transmembrane 4 L six family members (TM4SFs). Structurally, TM4SF1 …
[HTML][HTML] LNCaP Atlas: Gene expression associated with in vivoprogression to castration-recurrent prostate cancer
TL Romanuik, G Wang, O Morozova, A Delaney… - BMC medical …, 2010 - Springer
Background There is no cure for castration-recurrent prostate cancer (CRPC) and the
mechanisms underlying this stage of the disease are unknown. Methods We analyzed the …
mechanisms underlying this stage of the disease are unknown. Methods We analyzed the …
Unique patterns of molecular profiling between human prostate cancer LNCaP and PC‐3 cells
MG Dozmorov, RE Hurst, DJ Culkin, BP Kropp… - The …, 2009 - Wiley Online Library
BACKGROUND Human prostate cancer LNCaP and PC‐3 cell lines have been extensively
used to study prostate cancer progression and to develop therapeutic agents. Although …
used to study prostate cancer progression and to develop therapeutic agents. Although …
Ubiquitin‐based probes prepared by total synthesis to profile the activity of deubiquitinating enzymes
A de Jong, R Merkx, I Berlin, B Rodenko… - …, 2012 - Wiley Online Library
Epitope‐tagged active‐site‐directed probes are widely used to visualize the activity of
deubiquitinases (DUBs) in cell extracts, to investigate the specificity and potency of small …
deubiquitinases (DUBs) in cell extracts, to investigate the specificity and potency of small …
[HTML][HTML] Classification of early and late stage liver hepatocellular carcinoma patients from their genomics and epigenomics profiles
Background Liver Hepatocellular Carcinoma (LIHC) is one of the major cancers worldwide,
responsible for millions of premature deaths every year. Prediction of clinical staging is vital …
responsible for millions of premature deaths every year. Prediction of clinical staging is vital …