Nanostructured lipid carriers: Promising drug delivery systems for future clinics

A Beloqui, MÁ Solinís, A Rodríguez-Gascón… - … , biology and medicine, 2016 - Elsevier
During the past decade, the number of studies describing nanostructured lipid carriers
(NLCs)-based formulations has been dramatically increased. The raise in NLC exploitation …

Nanotoxicology applied to solid lipid nanoparticles and nanostructured lipid carriers–a systematic review of in vitro data

S Doktorovova, EB Souto, AM Silva - European Journal of Pharmaceutics …, 2014 - Elsevier
Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) were developed as
alternative to other colloidal carriers. They were designed to overcome lipid nanoemulsions …

Chitosan-coated nanostructured lipid carriers for transdermal delivery of tetrahydrocurcumin for breast cancer therapy

TH Truong, KP Alcantara, BPI Bulatao… - Carbohydrate …, 2022 - Elsevier
Chitosan (Ch)-coated nanostructured lipid carriers (NLCs) have great potential for
transdermal delivery with high localization of chemotherapeutics in breast cancer. This study …

Nano-formulations for transdermal drug delivery: A review

X Zhou, Y Hao, L Yuan, S Pradhan, K Shrestha… - Chinese Chemical …, 2018 - Elsevier
Transdermal drug delivery refers to a means of delivering drugs through the surface of the
skin for local or systemic treatment. The drug functions after absorption through the skin into …

[HTML][HTML] Nanostructured lipid carriers and their potential applications for versatile drug delivery via oral administration

VN Thuy, TV Van, AH Dao, BJ Lee - OpenNano, 2022 - Elsevier
Enteral administration is the most convenient route despite the gastrointestinal physiological
barriers. Nanostructured lipid carriers (NLCs) have emerged as a promising strategy for …

[HTML][HTML] Computational and experimental approaches for investigating nanoparticle-based drug delivery systems

M Ramezanpour, SSW Leung… - … et Biophysica Acta (BBA …, 2016 - Elsevier
Most therapeutic agents suffer from poor solubility, rapid clearance from the blood stream, a
lack of targeting, and often poor translocation ability across cell membranes. Drug/gene …

[HTML][HTML] Nanomaterials in skin regeneration and rejuvenation

E Bellu, S Medici, D Coradduzza, S Cruciani… - International journal of …, 2021 - mdpi.com
Skin is the external part of the human body; thus, it is exposed to outer stimuli leading to
injuries and damage, due to being the tissue mostly affected by wounds and aging that …

Rifabutin-loaded solid lipid nanoparticles for inhaled antitubercular therapy: Physicochemical and in vitro studies

DP Gaspar, V Faria, LMD Gonçalves, P Taboada… - International journal of …, 2016 - Elsevier
Systemic administration of antitubercular drugs can be complicated by off-target toxicity to
cells and tissues that are not infected by Mycobacterium tuberculosis. Delivery of …

Quality by Design (QbD)-enabled development of aceclofenac loaded-nano structured lipid carriers (NLCs): An improved dermatokinetic profile for inflammatory …

NK Garg, G Sharma, B Singh, P Nirbhavane… - International Journal of …, 2017 - Elsevier
Present study was designed to prepare and characterize aceclofenac loaded
nanostructured lipid carriers (NLCs) employing Quality by Design (QbD)-oriented approach …

Dermatokinetic assessment of luliconazole-loaded nanostructured lipid carriers (NLCs) for topical delivery: QbD-driven design, optimization, and in vitro and ex vivo …

A Mahmood, VK Rapalli, S Gorantla, T Waghule… - Drug Delivery and …, 2022 - Springer
The present study is concerned with the QbD-based design and development of
luliconazole-loaded nanostructured lipid carriers (NLCs) hydrogel for enhanced skin …