Apoptotic proteins with non-apoptotic activity: Expression and function in cancer

V Shoshan-Barmatz, T Arif, A Shteinfer-Kuzmine - Apoptosis, 2023 - Springer
Apoptosis is a process of programmed cell death in which a cell commits suicide while
maintaining the integrity and architecture of the tissue as a whole. Apoptosis involves …

Natural Anticancer Peptides from Marine Animal Species: Evidence from In Vitro Cell Model Systems

M Librizzi, C Martino, M Mauro, G Abruscato, V Arizza… - Cancers, 2023 - mdpi.com
Simple Summary Anticancer peptides are short aminoacidic chains, which display selective
cytotoxicity mostly against tumor, but not healthy, cells through interference with intracellular …

[HTML][HTML] Nanoplastic propels diet-induced NAFL to NASH via ER-mitochondrial tether-controlled redox switch

J Wei, J Liu, H Wang, K Wen, X Ni, Y Lin… - Journal of Hazardous …, 2024 - Elsevier
Nonalcoholic steatohepatitis (NASH) is multifactorial that lifestyle, genetic, and
environmental factors contribute to its onset and progression, thereby posing a challenge for …

Overexpression of the mitochondrial anti-viral signaling protein, MAVS, in cancers is associated with cell survival and inflammation

S Trishna, A Lavon, A Shteinfer-Kuzmine… - … Therapy-Nucleic Acids, 2023 - cell.com
Mitochondrial anti-viral signaling protein (MAVS) plays an important role in host defense
against viral infection via coordinating the activation of NF-κB and interferon regulatory …

Melatonin Exerts Prominent, Differential Epidermal and Dermal Anti-Aging Properties in Aged Human Eyelid Skin Ex Vivo

T Samra, T Gomez-Gomez, K Linowiecka… - International Journal of …, 2023 - mdpi.com
Human skin aging is associated with functional deterioration on multiple levels of
physiology, necessitating the development of effective skin senotherapeutics. The well …

Identification of neutrophil extracellular traps and crosstalk genes linking inflammatory bowel disease and osteoporosis by integrated bioinformatics analysis and …

G Xu, W Zhang, J Yang, N Sun, X Qu - Scientific Reports, 2023 - nature.com
Musculoskeletal deficits are among the most common extra-intestinal manifestations and
complications of inflammatory bowel disease (IBD). This study aimed to identify crosstalk …

Mitochondrial Mechanisms in Immunity and Inflammatory Conditions: Beyond Energy Management

S Alvarez, V Vanasco, JS Adán Areán… - Antioxidants & Redox …, 2024 - liebertpub.com
Significance: The growing importance of mitochondria in the immune response and
inflammation is multifaceted. Unraveling the different mechanisms by which mitochondria …

Neuroprotective Effects of N-methyl-(2S, 4R)-trans-4-hydroxy-L-proline (NMP) against Amyloid-β-Induced Alzheimer's Disease Mouse Model

J Ali, A Khan, JS Park, M Tahir, W Ahmad, K Choe… - Nutrients, 2023 - mdpi.com
Alzheimer's disease (AD), is a progressive neurodegenerative disorder that involves the
deposition of β-amyloid plaques and the clinical symptoms of confusion, memory loss, and …

Detrimental Roles of Hypoxia-Inducible Factor-1α in Severe Hypoxic Brain Diseases

YK Choi - International Journal of Molecular Sciences, 2024 - mdpi.com
Hypoxia stabilizes hypoxia-inducible factors (HIFs), facilitating adaptation to hypoxic
conditions. Appropriate hypoxia is pivotal for neurovascular regeneration and immune cell …

[HTML][HTML] Astaxanthin attenuated cigarette smoke extract-induced apoptosis via decreasing oxidative DNA damage in airway epithelium

H Tang, Y Zhang, Q Wang, Z Zeng, X Wang, Y Li… - Biomedicine & …, 2023 - Elsevier
Chronic obstructive pulmonary disease (COPD) is a lung inflammatory disease that is
associated with environmental allergic component exposure. Cigarette smoke is an …