The impact of estradiol on neurogenesis and cognitive functions in Alzheimer's disease

S Sahab-Negah, V Hajali, HR Moradi… - Cellular and Molecular …, 2020 - Springer
Alzheimer's disease (AD) is described as cognitive and memory impairments with a sex-
related epidemiological profile, affecting two times more women than men. There is …

[HTML][HTML] Neuroimaging of mouse models of Alzheimer's disease

A Jullienne, MV Trinh, A Obenaus - Biomedicines, 2022 - mdpi.com
Magnetic resonance imaging (MRI) and positron emission tomography (PET) have made
great strides in the diagnosis and our understanding of Alzheimer's Disease (AD). Despite …

Combined effects of aerobic exercise and 40-Hz light flicker exposure on early cognitive impairments in Alzheimer's disease of 3× Tg mice

SS Park, HS Park, CJ Kim, SS Baek… - Journal of Applied …, 2022 - journals.physiology.org
Alzheimer's disease (AD) is a progressive degenerative brain disease and the primary
cause of dementia. At an early stage, AD is generally characterized by short-term memory …

Chronic deep brain stimulation in an Alzheimer's disease mouse model enhances memory and reduces pathological hallmarks

A Mann, E Gondard, D Tampellini, JAT Milsted… - Brain stimulation, 2018 - Elsevier
Background Alzheimer's disease (AD) is a progressive degenerative disorder that currently
remains extremely disabling. Recent work has shown that deep brain stimulation (DBS) has …

A longitudinal multimodal in vivo molecular imaging study of the 3xTg-AD mouse model shows progressive early hippocampal and taurine loss

S Chiquita, M Ribeiro, J Castelhano… - Human molecular …, 2019 - academic.oup.com
The understanding of the natural history of Alzheimer's disease (AD) and temporal
trajectories of in vivo molecular mechanisms requires longitudinal approaches. A behavioral …

[HTML][HTML] Ganoderma lucidum aqueous extract prevents hypobaric hypoxia induced memory deficit by modulating neurotransmission, neuroplasticity and maintaining …

P Sharma, R Tulsawani - Scientific Reports, 2020 - nature.com
Oxidative stress due to hypobaric hypoxia at extreme altitudes causes severe neuronal
damage and irreversible cognitive loss. Owing to contraindications of current drug therapies …

[HTML][HTML] Fluoxetine attenuates the impairment of spatial learning ability and prevents neuron loss in middle-aged APPswe/PSEN1dE9 double transgenic Alzheimer's …

J Ma, Y Gao, L Jiang, F Chao, W Huang, C Zhou… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Selective serotonin reuptake inhibitors (SSRIs) have been reported to increase cognitive
performance in some clinical studies of Alzheimer's disease (AD). However, there is a lack of …

Molecular mechanisms of altered adult hippocampal neurogenesis in Alzheimer's disease

H Liu, H Zhang, Y Ma - Mechanisms of ageing and development, 2021 - Elsevier
Alzheimer's disease (AD) is the most common cause of dementia globally. AD is a
progressive neurodegenerative disorder, eventually manifesting as severe cognitive …

Xanthoceras sorbifolia extracts ameliorate dendritic spine deficiency and cognitive decline via upregulation of BDNF expression in a rat model of Alzheimer's disease

Y Li, J Xu, P Xu, S Song, P Liu, T Chi, X Ji, G Jin… - Neuroscience …, 2016 - Elsevier
Xanthoceras sorbifolia, a traditional Chinese folk medicine with anti-inflammatory effects,
has been used for a long time in China, especially in the Inner Mongolian area for the …

The neuroprotective effect of deep brain stimulation at nucleus basalis of Meynert in transgenic mice with Alzheimer's disease

C Huang, H Chu, Y Ma, Z Zhou, C Dai, X Huang… - Brain stimulation, 2019 - Elsevier
Background Alzheimer's disease (AD) is the most common type of dementia and mainly
treated by drugs, while the therapeutic outcomes are very limited. This study aimed to …