Immunosuppressive drugs in kidney transplantation: impact on patient survival, and incidence of cardiovascular disease, malignancy and infection
R Marcén - Drugs, 2009 - Springer
Renal transplant recipients have increased mortality rates when compared with the general
population. The new immunosuppressive drugs have improved short-term patient survival …
population. The new immunosuppressive drugs have improved short-term patient survival …
Manifestations of human cytomegalovirus infection: proposed mechanisms of acute and chronic disease
W Britt - Human cytomegalovirus, 2008 - Springer
Infections with human cytomegalovirus (HCMV) are a major cause of morbidity and mortality
in humans with acquired or developmental deficits in innate and adaptive immunity. In the …
in humans with acquired or developmental deficits in innate and adaptive immunity. In the …
Cytomegalovirus reactivation in critically ill immunocompetent patients
AP Limaye, KA Kirby, GD Rubenfeld, WM Leisenring… - Jama, 2008 - jamanetwork.com
Context Cytomegalovirus (CMV) infection is associated with adverse clinical outcomes in
immunosuppressed persons, but the incidence and association of CMV reactivation with …
immunosuppressed persons, but the incidence and association of CMV reactivation with …
International consensus guidelines on the management of cytomegalovirus in solid organ transplantation
Cytomegalovirus (CMV) remains one of the most common infections after solid organ
transplantation, resulting in significant morbidity, graft loss, and occasional mortality …
transplantation, resulting in significant morbidity, graft loss, and occasional mortality …
Progress and challenges in the prevention, diagnosis, and management of cytomegalovirus infection in transplantation
Hosts with compromised or naive immune systems, such as individuals living with HIV/AIDS,
transplant recipients, and fetuses, are at the highest risk for complications from …
transplant recipients, and fetuses, are at the highest risk for complications from …
[HTML][HTML] Prophylactic versus preemptive oral valganciclovir for the management of cytomegalovirus infection in adult renal transplant recipients
JA Khoury, GA Storch, DL Bohl, RM Schuessler… - American Journal of …, 2006 - Elsevier
Prophylaxis reduces cytomegalovirus (CMV) disease, but is associated with increased costs
and risks for side effects, viral resistance and late onset CMV disease. Preemptive therapy …
and risks for side effects, viral resistance and late onset CMV disease. Preemptive therapy …
[HTML][HTML] Improvement in long-term renal graft survival due to CMV prophylaxis with oral ganciclovir: results of a randomized clinical trial
V Kliem, L Fricke, T Wollbrink, M Burg… - American Journal of …, 2008 - Elsevier
Oral ganciclovir prophylaxis and intravenous preemptive therapy are competitive
approaches to prevent cytomegalovirus (CMV) disease after renal transplantation. This trial …
approaches to prevent cytomegalovirus (CMV) disease after renal transplantation. This trial …
Delayed-onset primary cytomegalovirus disease and the risk of allograft failure and mortality after kidney transplantation
SK Arthurs, AJ Eid, RA Pedersen… - Clinical infectious …, 2008 - academic.oup.com
Background. During the contemporary era of antiviral prophylaxis, the impact of delayed-
onset primary cytomegalovirus (CMV) disease on the outcome of kidney transplantation is …
onset primary cytomegalovirus (CMV) disease on the outcome of kidney transplantation is …
[HTML][HTML] The 'indirect'effects of cytomegalovirus infection
RB Freeman Jr - American Journal of Transplantation, 2009 - Elsevier
Cytomegalovirus (CMV) remains the most important infection in the immunocompromized
host even in the era of effective therapy. CMV is usually acquired early in life and can be …
host even in the era of effective therapy. CMV is usually acquired early in life and can be …
[HTML][HTML] Two-year outcomes in de novo renal transplant recipients receiving everolimus-facilitated calcineurin inhibitor reduction regimen from the TRANSFORM study
SP Berger, C Sommerer, O Witzke, H Tedesco… - American Journal of …, 2019 - Elsevier
TRANSFORM (TRANSplant eFficacy and safety Outcomes with an eveRolimus-based
regiMen) was a 24-month, prospective, open-label trial in 2037 de novo renal transplant …
regiMen) was a 24-month, prospective, open-label trial in 2037 de novo renal transplant …