British Society of Gastroenterology consensus guidelines on the management of inflammatory bowel disease in adults

CA Lamb, NA Kennedy, T Raine, PA Hendy, PJ Smith… - Gut, 2019 - gut.bmj.com
Ulcerative colitis and Crohn's disease are the principal forms of inflammatory bowel disease.
Both represent chronic inflammation of the gastrointestinal tract, which displays …

Revisiting fibrosis in inflammatory bowel disease: the gut thickens

S D'Alessio, F Ungaro, D Noviello, S Lovisa… - Nature Reviews …, 2022 - nature.com
Intestinal fibrosis, which is usually the consequence of chronic inflammation, is a common
complication of inflammatory bowel disease (IBD), including Crohn's disease and ulcerative …

ACG clinical guideline: management of Crohn's disease in adults

GR Lichtenstein, EV Loftus, KL Isaacs… - Official journal of the …, 2018 - journals.lww.com
Crohn's disease is an idiopathic inflammatory disorder of unknown etiology with genetic,
immunologic, and environmental influences. The incidence of Crohn's disease has steadily …

Chemically induced mouse models of acute and chronic intestinal inflammation

S Wirtz, V Popp, M Kindermann, K Gerlach… - Nature protocols, 2017 - nature.com
Inflammatory bowel diseases (IBDs) result in diarrhea and abdominal pain with further
potential complications such as tissue fibrosis and stenosis. Animal models help in …

Immunopathogenesis of IBD: current state of the art

HSP De Souza, C Fiocchi - Nature reviews Gastroenterology & …, 2016 - nature.com
IBD is a chronic inflammatory condition of the gastrointestinal tract encompassing two main
clinical entities: Crohn's disease and ulcerative colitis. Although Crohn's disease and …

Prediction of complicated disease course for children newly diagnosed with Crohn's disease: a multicentre inception cohort study

S Kugathasan, LA Denson, TD Walters, MO Kim… - The Lancet, 2017 - thelancet.com
Background Stricturing and penetrating complications account for substantial morbidity and
health-care costs in paediatric and adult onset Crohn's disease. Validated models to predict …

ECCO-ESGAR Guideline for Diagnostic Assessment in IBD Part 2: IBD scores and general principles and technical aspects

A Sturm, C Maaser, E Calabrese… - Journal of Crohn's …, 2019 - academic.oup.com
There are several scoring systems presently available to classify disease severity in
ulcerative colitis [UC] within the multiple domains of disease activity, which aid objective …

Mechanisms, management, and treatment of fibrosis in patients with inflammatory bowel diseases

F Rieder, C Fiocchi, G Rogler - Gastroenterology, 2017 - Elsevier
In the last 10 years, we have learned much about the pathogenesis, diagnosis, and
management of intestinal fibrosis in patients with inflammatory bowel diseases. Just a …

Consensus recommendations for evaluation, interpretation, and utilization of computed tomography and magnetic resonance enterography in patients with small …

DH Bruining, EM Zimmermann, EV Loftus Jr… - Radiology, 2018 - pubs.rsna.org
Computed tomography and magnetic resonance enterography have become routine small
bowel imaging tests to evaluate patients with established or suspected Crohn's disease, but …

Efficacy of adalimumab in patients with Crohn's disease and symptomatic small bowel stricture: a multicentre, prospective, observational cohort (CREOLE) study

Y Bouhnik, F Carbonnel, D Laharie, C Stefanescu… - Gut, 2018 - gut.bmj.com
Objective The efficacy of anti-tumour necrosis factors (anti-TNFs) in patients with Crohn's
disease (CD) and symptomatic small bowel stricture (SSBS) is controversial. The aim of this …