3′-untranslated regions (3′-UTRs) are the noncoding parts of mRNAs. Compared to
yeast, in humans, median 3′-UTR length has expanded approximately tenfold alongside …

Embryonic development requires tight control of gene expression levels, activity, and
localisation. This control is coordinated by multiple levels of regulation on DNA, RNA and …

RNA viruses interact with a wide range of cellular RNA-binding proteins (RBPs) during their
life cycle. The prevalence of these host–virus interactions has been highlighted by new …

Protein kinase C (PKC) is a family of phospholipid‐dependent serine/threonine kinases,
which can be further classified into three PKC isozymes subfamilies: conventional or classic …

The RNA-binding protein (RBP) HuR is one of the most widely studied regulators of the
eukaryotic posttranscriptional gene expression and it plays a physiological role in mediating …

The mechanisms of de novo gene expression and translation of specific gene transcripts
have long been known to support long-lasting changes in synaptic plasticity and behavioral …

The impact of the RNA-binding protein HuR for the post-transcriptional deregulation of tumor-
relevant genes is well established. Despite of elevations in HuR expression levels, an …

The accumulation of 3'untranslated region (3'-UTR), AU-rich element (ARE) containing
mRNAs, are predominantly controlled at the post-transcriptional level. Regulation appears to …

Introduction: The regulation of intracellular functions in mammalian cells involves close
coordination of cellular processes. During recent years it has become evident that the …

Colorectal cancer (CRC) is one of the most common cancers that is characterized by a high
mortality due to the strong metastatic potential of the primary tumor and the high rate of …