Mapping of quantitative trait loci for blood pressure and cardiac mass in the rat by genome scanning of recombinant inbred strains.
M Pravenec, D Gauguier, JJ Schott… - The Journal of …, 1995 - Am Soc Clin Investig
In the HXB and BXH recombinant inbred strains derived from the spontaneously
hypertensive rat and the normotensive Brown Norway rat, we determined the strain …
hypertensive rat and the normotensive Brown Norway rat, we determined the strain …
Mechanisms of the circadian regulation of β-adrenoceptor density and adenylyl cyclase activity in cardiac tissue from normotensive and spontaneously hypertensive …
K Witte, R Parsa-Parsi, M Vobig, B Lemmer - Journal of molecular and …, 1995 - Elsevier
Circadian variation in β-adrenoceptor density and adenylyl cyclase activity was studied in
myocardium from normotensive Wistar-Kyoto rats (WKY) and spontaneously hypertensive …
myocardium from normotensive Wistar-Kyoto rats (WKY) and spontaneously hypertensive …
Effects of renin gene transfer on blood pressure and renin gene expression in a congenic strain of Dahl salt-resistant rats.
EM St Lezin, M Pravenec, AL Wong… - The Journal of …, 1996 - Am Soc Clin Investig
To investigate whether a BP-regulatory locus exists in the vicinity of the renin locus on rat
chromosome 13, we transferred this chromosome segment from the Dahl salt-sensitive (S) …
chromosome 13, we transferred this chromosome segment from the Dahl salt-sensitive (S) …
Altered β-Adrenergic Regulation of Na-K-C1 Cotransport in Cultured Smooth Muscle Cells From the Aorta of Spontaneously Hypertensive Rats: Role of the …
SN Orlov, J Tremblay, P Hamet - American journal of …, 1995 - academic.oup.com
To verify the hypothesis of Na-K-Cl cotransport (COTR) involvement in ion transport
abnormalities as revealed in vascular smooth muscle cells (VSMC) of spontaneously …
abnormalities as revealed in vascular smooth muscle cells (VSMC) of spontaneously …
Association of salt sensitivity in rats with genes of the major histocompatibility complex.
J Kunes, J Zicha - Hypertension, 1994 - Am Heart Assoc
Dietary sodium intake has long been considered an important factor in the genesis and
maintenance of hypertension in both humans and experimental animals. To identify the …
maintenance of hypertension in both humans and experimental animals. To identify the …
Pathogenesis of hypertension: genetic and environmental factors
AB Weder - Atlas of Hypertension, 2005 - Springer
NK Hollenberg (ed.), Atlas of Hypertension © Springer Science+Business Media New York
2003 Page 1 NK Hollenberg (ed.), Atlas of Hypertension © Springer Science+Business Media …
2003 Page 1 NK Hollenberg (ed.), Atlas of Hypertension © Springer Science+Business Media …
[图书][B] Molecular Genetics & Gene Therapy of Cardiovascular Diseases
SC Mockrin - 1996 - taylorfrancis.com
Provides detailed discussions of the most recent developments in gene mapping and
manipulation to improve the diagnosis, detection, prevention, and treatment of various …
manipulation to improve the diagnosis, detection, prevention, and treatment of various …
Using animal models to dissect the genetics of complex traits
JH Krege, TW Kurtz, O Smithies - … AND CLINICAL CARDIOLOGY, 1996 - books.google.com
Animal models provide excellent systems for studying environmental and genetic factors that
cause complex (multifactorial) diseases such as hypertension, atherosclerosis, stroke, and …
cause complex (multifactorial) diseases such as hypertension, atherosclerosis, stroke, and …
Identification of defective Cd36 as a quantitative trait locus for cardiovascular risk factor clustering in the spontaneously hypertensive rat
M Pravenec, V Landa, V Zídek, V Kren - Current Genomics, 2001 - ingentaconnect.com
It was demonstrated that a gene or genes responsible for a whole spectrum of
cardiovascular risk factors map to a limited segment of the centromeric region of rat …
cardiovascular risk factors map to a limited segment of the centromeric region of rat …
[图书][B] Development of Congenic Lines and Application of Physical Mapping Strategies for the Dissection of Blood Pressure Quantitative Trait Loci in the Stroke-Prone …
CDN Deus - 2000 - search.proquest.com
Human essential hypertension is a complex, multifactorial, quantitative trait under polygenic
control. Several strategies have been developed over the last decade to dissect genetic …
control. Several strategies have been developed over the last decade to dissect genetic …