miRNAs role in cervical cancer pathogenesis and targeted therapy: Signaling pathways interplay

AS Doghish, MA Ali, SS Elyan, MA Elrebehy… - … -Research and Practice, 2023 - Elsevier
Cervical cancer (CC) is the primary cause of cancer deaths in underdeveloped countries.
The persistence of infection with high-risk human papillomavirus (HPV) is a significant …

HPV16 and HPV18 genome structure, expression, and post-transcriptional regulation

L Yu, V Majerciak, ZM Zheng - International journal of molecular sciences, 2022 - mdpi.com
Human papillomaviruses (HPV) are a group of small non-enveloped DNA viruses whose
infection causes benign tumors or cancers. HPV16 and HPV18, the two most common high …

Resveratrol against cervical cancer: Evidence from in vitro and in vivo studies

M Nadile, MI Retsidou, K Gioti, A Beloukas, E Tsiani - Nutrients, 2022 - mdpi.com
Cervical cancer affects many women worldwide, with more than 500,000 cases diagnosed
and approximately 300,000 deaths each year. Resveratrol is a natural substance of the …

Human papilloma virus: an unraveled enigma of universal burden of malignancies

I Khan, R Harshithkumar, A More, A Mukherjee - Pathogens, 2023 - mdpi.com
HPV, or Human Papilloma Virus, has been the primary causative agent of genital warts and
cervical cancer worldwide. It is a sexually transmitted infection mainly affecting women of …

Targeting genetic modifiers of HBG gene expression in sickle cell disease: the miRNA option

A Starlard-Davenport, Q Gu, BS Pace - Molecular Diagnosis & Therapy, 2022 - Springer
Sickle cell disease (SCD) is one of the most common inherited hemoglobinopathy disorders
that affects millions of people worldwide. Reactivation of HBG (HBG1, HBG2) gene …

[HTML][HTML] MiR-95-3p acts as a prognostic marker and promotes cervical cancer progression by targeting VCAM1

S Feng, Y Lu, L Sun, S Hao, Z Liu, F Yang… - Annals of …, 2022 - ncbi.nlm.nih.gov
Background Cervical cancer patients have a high risk of metastasis and a poor prognosis
with shorter disease-free survival. Thus, novel biomarkers and feasible therapies urgently …

[HTML][HTML] Revealing PACMA 31 as a new chemical type TrxR inhibitor to promote cancer cell apoptosis

Q Xu, J Zhang, Z Zhao, Y Chu, J Fang - Biochimica et Biophysica Acta (BBA …, 2022 - Elsevier
Thioredoxin reductase (TrxR) is a pivotal regulator of redox homeostasis, while
dysregulation of redox homeostasis is a hallmark for cancer cells. Thus, there is …

miR‐96‐5p regulates cervical cancer cell resistance to cisplatin by inhibiting lncRNA TRIM52‐AS1 and promoting IGF2BP2

EY Wu, LP Huang, JH Bao - The Kaohsiung Journal of Medical …, 2022 - Wiley Online Library
MicroRNA (miRNA) and long noncoding RNA (lncRNA) are both regulators of cancer
progression. This study sought to discuss the functional mechanism of miR‐96‐5p/lncRNA …

Overview of miR-106a Regulatory roles: from Cancer to Aging

M Daneshpour, A Ghadimi-Daresajini - Bioengineering, 2023 - mdpi.com
MicroRNAs (miRNAs) comprise a class of non-coding RNA with extensive regulatory
functions within cells. MiR-106a is recognized for its super-regulatory roles in vital …

Human papillomavirus type 16 E7 promotes cell viability and migration in cervical cancer by regulating the miR-23a/HOXC8 axis

Y Chen, L Sun, L Li - Journal of Obstetrics and Gynaecology, 2024 - Taylor & Francis
Background Human papillomavirus (HPV) is a risk factor for the occurrence of cervical
cancer (CC). Here, we aimed to explore the role of HPV16 in CC and identify the underlying …