Cadherin-mediated cell–cell adhesion and signaling in the skeleton
PJ Marie, E Haÿ, D Modrowski, L Revollo… - Calcified tissue …, 2014 - Springer
Direct cell-to-cell interactions via cell adhesion molecules, in particular cadherins, are critical
for morphogenesis, tissue architecture, and cell sorting and differentiation. Partially …
for morphogenesis, tissue architecture, and cell sorting and differentiation. Partially …
Molecular mechanisms of osteoblast/osteocyte regulation by connexin43
JP Stains, MP Watkins, SK Grimston, C Hebert… - Calcified tissue …, 2014 - Springer
Osteoblasts, osteocytes, and osteoprogenitor cells are interconnected into a functional
network by gap junctions formed primarily by connexin43 (Cx43). Over the past two …
network by gap junctions formed primarily by connexin43 (Cx43). Over the past two …
Osteoblast connexin43 modulates skeletal architecture by regulating both arms of bone remodeling
M Watkins, SK Grimston, JY Norris… - Molecular biology of …, 2011 - Am Soc Cell Biol
Connexin43 (Cx43) has an important role in skeletal homeostasis, and Cx43 gene (Gja1)
mutations have been linked to oculodentodigital dysplasia (ODDD), a human disorder …
mutations have been linked to oculodentodigital dysplasia (ODDD), a human disorder …
Investigation of bone resorption within a cortical basic multicellular unit using a lattice-based computational model
PR Buenzli, J Jeon, P Pivonka, DW Smith… - Bone, 2012 - Elsevier
In this paper we develop a lattice-based computational model focused on bone resorption
by osteoclasts in a single cortical basic multicellular unit (BMU). Our model takes into …
by osteoclasts in a single cortical basic multicellular unit (BMU). Our model takes into …
[HTML][HTML] Connexin43 modulates post-natal cortical bone modeling and mechano-responsiveness
Recent advances have established connexin43 (Cx43) as a key regulator of osteoblast
function and of bone response to mechanical stimuli. Work by independent laboratories has …
function and of bone response to mechanical stimuli. Work by independent laboratories has …
Pharmacophysiology of bone and spinal fusion
Background context In recent years, the number of complex spinal surgeries has increased
significantly in the elderly population, where the prevalence of low bone density is highest …
significantly in the elderly population, where the prevalence of low bone density is highest …
Osteocytes up-regulate the terminal differentiation of pre-osteoblasts via gap junctions
Y Nishikawa, Y Akiyama, K Yamamoto… - Biochemical and …, 2015 - Elsevier
We examined cell-to-cell interaction between pre-osteoblasts and osteocytes using MC3T3-
E1 and MLO-Y4, respectively. First, GFP expressing MC3T3-E1 (E1-GFP) cells were …
E1 and MLO-Y4, respectively. First, GFP expressing MC3T3-E1 (E1-GFP) cells were …
Papel del receptor de tipo I de la parathormona (PTH1R) y del cilio primario en la mecanotransducción ósea y en el reclutamiento y la diferenciación de precursores …
I Tirado Cabrera - repositorioinstitucional.ceu.es
El hueso es un tejido dinámico que se remodela continuamente ante una gran variedad de
estímulos, entre ellos el estímulo mecánico. Los osteocitos responden a las fuerzas …
estímulos, entre ellos el estímulo mecánico. Los osteocitos responden a las fuerzas …
[图书][B] Examining novel factors that influence contact-dependent osteoblast and osteoclast differentiation
CE Fiorino - 2016 - search.proquest.com
A dynamic equilibrium between bone destruction by osteoclasts and bone formation by
osteoblasts is responsible for the maintenance of bone integrity, mineral homeostasis and …
osteoblasts is responsible for the maintenance of bone integrity, mineral homeostasis and …