The skin microbiome: current landscape and future opportunities

P Smythe, HN Wilkinson - International journal of molecular sciences, 2023 - mdpi.com
Our skin is the largest organ of the body, serving as an important barrier against the harsh
extrinsic environment. Alongside preventing desiccation, chemical damage and …

Diabetic wound healing in soft and hard oral tissues

KI Ko, A Sculean, DT Graves - Translational Research, 2021 - Elsevier
There is significant interest in understanding the cellular mechanisms responsible for
expedited healing response in various oral tissues and how they are impacted by systemic …

Chronic wounds: Treatment consensus

E Eriksson, PY Liu, GS Schultz… - Wound repair and …, 2022 - Wiley Online Library
Abstract The Wound Healing Foundation (WHF) recognised a need for an unbiased
consensus on the best treatment of chronic wounds. A panel of 13 experts were invited to a …

Biological macromolecules-based nanoformulation in improving wound healing and bacterial biofilm-associated infection: a review

SS Garg, R Dubey, S Sharma, A Vyas… - International Journal of …, 2023 - Elsevier
A chronic wound is a serious complication associated with diabetes mellitus and is difficult to
heal due to high glucose levels, oxidative stress, and biofilm-associated microbial infection …

Colonizing microbiota is associated with clinical outcomes in diabetic wound healing

G Wang, Z Lin, Y Li, L Chen, SK Reddy, Z Hu… - Advanced drug delivery …, 2023 - Elsevier
With the development of society and the improvement of life quality, more than 500 million
people are affected by diabetes. More than 10% of people with diabetes will suffer from …

Keratinocyte function in normal and diabetic wounds and modulation by FOXO1

Y Wang, DT Graves - Journal of Diabetes Research, 2020 - Wiley Online Library
Diabetes has a significant and negative impact on wound healing, which involves complex
interactions between multiple cell types. Keratinocytes play a crucial role in the healing …

Signaling pathways associated with chronic wound progression: A systems biology approach

P Basu, M Martins-Green - Antioxidants, 2022 - mdpi.com
Previously we have shown that several oxidative stress-driven pathways in cutaneous
chronic wounds are dysregulated in the first 48 h post-wounding. Here, we performed an …

The Epidermal keratinocyte as a therapeutic target for management of diabetic wounds

WC Fang, CCE Lan - International Journal of Molecular Sciences, 2023 - mdpi.com
Diabetes mellitus (DM) is an important cause of chronic wounds and non-traumatic
amputation. The prevalence and number of cases of diabetic mellitus are increasing …

Microbiological effects in patients with leg ulcers and diabetic foot treated with Lucilia sericata larvae

Z Szczepanowski, BO Grabarek… - International Wound …, 2022 - Wiley Online Library
Lucilia sericata bottle fly worms can be used to heal infected, chronic, or necrotic wounds,
including those associated with ulceration and diabetic foot. The study aimed to evaluate …

Using systems biology approaches to identify signalling pathways activated during chronic wound initiation

P Basu, JH Kim, S Saeed… - Wound Repair and …, 2021 - Wiley Online Library
Chronic wounds are a significant health problem worldwide. However, nothing is known
about how chronic wounds initiate and develop. Here we use a chronic wound model in …